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[기고] Effective vaccine application for the control of major PRDC-causing pathogens

1. PRDC pathogens

‘Porcine respiratory disease complex (PRDC)’ is a disease that is difficult for farmers to solve on their own because there are various pathogens associated with the disease.in.

In Korea, after infection with Mycoplasma hyopneumoniae, porcine circovirus type 2 (PCV2), and porcine reproductive and respiratory syndrome virus (PRRS) as primary pathogens, Pasteurella, secondary pathogen It is caused by a complex infection with Pasteurella multocida, Glaesserella parasuis, Trueperella pyogenes, and Actinobacillus Pleuropneumoniae.

As various pathogens are infected, the disease is difficult to prevent or treat, and develops chronically, causing huge economic damage to farms. In order to fundamentally solve the swine respiratory complex disease, it is necessary to firstly understand the interaction of pathogens and secondly the interaction of vaccines. do.

2. Pathogen interaction

Looking at the interaction of the three pathogens, which is problematic in Korea, when mycoplasma-infected pigs are infected with ‘Porcine Reproductive and Respiratory Syndrome Virus’ or ‘Porcine Circovirus’ in a complex manner, clinical symptoms and lesions are enlarged. In addition, when pigs infected with porcine reproductive and respiratory syndrome virus are co-infected with porcine circovirus, clinical symptoms and lesions are magnified.

3. Vaccine interactions

By understanding the interaction of these vaccines based on pathogen interaction, farmers can easily decide which vaccine should be given priority.

Vaccination with a mycoplasma vaccine provides additional protection against porcine reproductive and respiratory syndrome virus. On the other hand, vaccination with mycoplasma vaccine has no additional protective effect against porcine circovirus. In addition, based on the interaction between porcine reproductive and respiratory syndrome virus and porcine circovirus, vaccination with porcine reproductive and respiratory syndrome virus appears to help in additional prevention of porcine circovirus.

4. PRDC answer

There are two solutions for swine respiratory complex disease using vaccines and antibiotics, but vaccines are mainly used on farms due to antibiotic residue and resistance problems.

Analyzing the previously mentioned interactions between pathogens and vaccine interactions, it is easy to provide an answer. In order to effectively prevent the three pathogens causing problems in Korea, First the most effective mycoplasma vaccine, then the porcine circo vaccine, and finally the porcine reproductive and respiratory syndrome vaccine. do. In particular, since the effect of mycoplasma on porcine reproductive and respiratory syndrome virus is high, an effective mycoplasma vaccine must be selected and vaccinated to prevent pneumonia caused by mycoplasma and also prevent porcine reproductive and respiratory syndrome.

In the future, we would like to present questions related to PRDC in the field and seek answers.

addresses

(1) Kim J, Chung HK, Chae C: Association of porcine circovirus 2 with porcine respiratory disease complex. The Veterinary Journal 166:251-256, 2003

(2) Field C: Porcine respiratory disease complex: Interaction of vaccination and porcine circovirus type 2, porcine reproductive and respiratory syndrome virus, and Mycoplasma hyopneumoniae. The Veterinary Journal 212:1-6, 2016

※ If you have any questions regarding the above contribution, please contact Seva Korea (070. 8277. 4747 / Kakao Talk Channel: Seva Korea / cevakorea@ceva.com).

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