[아이뉴스24 정종오 기자] Based on a hybrid microstructure that mimics the soles of a frog, a clean bio-insertable electronic patch has been developed that does not have any chemical residues during point and detachment. By applying this, various biosignals can be identified.
The National Research Foundation of Korea (Chairman Gwang-bok Lee) is a research team led by Professor Bang Chang-hyeon of Sungkyunkwan University and Dong-hee Son’s team (first author, Dr. Dawan Kim of Sungkyunkwan University, Dr. Kangil Song of Daegu Gyeongbuk Advanced Medical Industry Promotion Foundation) through joint research, announced on the 26th that it has developed a biocompatible electronic patch that can maintain a high adhesion state.
The bioadhesive material that mimics the sole of a frog induces adhesion based on hydrogen bonding (physical static electricity), capillary force and suction stress (mechanical interaction). It is designed to have stable adhesion to biological tissues where body fluids are always present and no chemical residues when detached.
Existing bio-insertable electronic patches were mainly attached using medical sutures or bio-adhesive chemical materials. When medical sutures are used, there is a burden of additional organ damage to the patient. In the case of using a chemical adhesive, there was a problem with a high possibility of adverse reactions such as biological rejection or adhesion as residues generated during point and desorption.
The research team first identified the surface adhesion, electrostatic force, and thermodynamic equilibrium mechanisms of microstructure-based elastic polymers and hydrogels (hybrid adhesive materials) that mimic frog soles. An electronic patch with sustainable bio-tissue adhesion without chemical residues on the surface of the living body was presented.
Long-term reliable for electrophysiological signals (electrocardiogram, electromyography, electroencephalogram, etc.) It was confirmed that the measurement was possible.
It is expected that practical application will be possible after continuous safety verification through animal experiments.
Professor Bang Chang-hyeon said, “We will continue research that can be applied to various medical and industrial fields as well as solving various problems we have by observing and analyzing the wise ways of living things to adapt to the environment and survive.”
The research result (the paper title: Electrostatic-mechanical synergistic in situ multiscale tissue adhesion for sustainable residue-free bioelectronics interface) was published online on November 15, 2021 in the international scientific journal ‘Advanced Materials’./Sejong = Reporter Jeong Jong-oh ([email protected])