(Taiwan English News/Comprehensive Report by Zhu Mingzhu) Latest research in the United States has found that “pre-diabetic” adults who supplement with more vitamin D are associated with a lower risk of developing type 2 diabetes. The study was published in the “Annals of Internal Medicine” on the 7th.
To assess whether taking vitamin D can reduce the risk of diabetes in patients with “pre-diabetic symptoms”, researchers from Tufts Medical Center in Massachusetts, USA, recruited 4190 adult subjects and randomly assigned them After 3 experimental group and 1 control group, clinical trials were conducted for 3 years.
According to the study report, a total of 2,097 adults were included in the experimental group (taking vitamin D), of which 475 had “pre-diabetic symptoms”; two groups used inactive vitamin D3, and the other group used active vitamin D. Of the 2,093 people in the control group (taking a placebo), 524 had “prediabetic symptoms.”
The results of the mixed analysis showed that compared to the placebo group, the vitamin D supplement group reduced the relative risk of diabetes by approximately 15%, and the absolute risk was reduced by 3.3%, even allows patients with abnormal blood sugar to return to normal blood sugar.
So the study authors, extrapolating their findings to more than 374 million adults with “prediabetes” worldwide, estimated that vitamin D supplementation could delay the onset of diabetes in more than 10 million people.
In this regard, Li Tingwei, director of the Metabolism Department of the Department of Internal Medicine of Wanfang Hospital, Ou Hongyi, director of the Chengda Hospital Diabetes Prevention Center, and Xie Boxuan, professor of Physiology and Biophysics at the National Defense Medical College, all present their analysis. Experts pointed out that the study used a high dose of vitamin D, which is not suitable for ordinary people, and a high dose of vitamin D can increase the risk of hypercalcemia, hyperuria or kidney stones.
Ou Hongyi said that although the study results indicate that only in groups with low or insufficient blood vitamin D levels, vitamin D supplementation may have the benefit of preventing “pre-diabetes” from progressing to diabetes, but recalled that in the study, vitamin D supplementation was seen in patients Afterwards, the average blood levels achieved were higher than the generally recognized safe range, and even reached levels considered “potentially harmful” in the past. In terms of blood sugar balance, it is necessary to consider what is a reasonable concentration of vitamin D.
Xie Boxuan said the subjects of the study were patients “with pre-diabetic symptoms”, rather than results the public can refer to. Therefore, this study does not prove that vitamin D supplementation in the general public can effectively reduce the risk of diabetes.
In addition, the pre-diabetic patients in the study used vitamin D doses of up to 1200 international units (IU) and maintained a high blood vitamin D concentration, which appeared to reduce the incidence of diabetes, but long-term use could cause hypercalcemia easily. and hyperhemuria, etc. associated toxic reactions.
Xie Boxuan added that the recommended daily dietary dose of vitamin D is 400 to 600 international units (IU), and this dose range cannot reach the dose that effectively reduces the incidence of diabetes in the research.
Li Tingwei pointed out that the study analyzed active and inactive vitamin D together He felt a little suspicious, because inactive vitamin D3 can be used as a nutritional supplement for the general public, but active vitamin D is being prescribed by dangerous doctors, it is recommended to consult a professional doctor first.
Finally, Hongyi Ou concluded that although the research provides scientific evidence that vitamin D can prevent “pre-diabetes” from progressing to diabetes, the benefits are limited to “pre-diabetes” patients having u strict screening, not the general public. Therefore, he suggested that the public need not rush to supplement with vitamin D, and let more research reports in the future verify these results and safety.
※ Source: Taiwan Technology Media Center ※
American study says vitamin D can prevent diabetes Experts remind: Excessive use can increase the risk of hypercalcemia and hyperuria
