The British royal family’s powerful hair loss and baldness genes have spared King Charles III, Prince Andrew, Prince Edward, Prince William, Harry, etc. The study identified the source of the royal family’s hair loss as coming from the Queen’s husband, Prince Philip In the patrilineal family, he was originally a Greek prince, and his father and grandfather were bald.
Now the outside world is starting to pay more attention and worry that Prince George’s forehead hairline is clearly a little too high. After all, how is the mechanism of hereditary hair loss formed?
Hereditary alopecia is a male hormone alopecia, which originates from testosterone in the body under the action of 5α-reductase to form the male hormone DHT (ie dihydrotestosterone, which is the culprit of hair loss), DHT binds to androgen receptors of follicle cells scalp hair. After that, the hair follicles will shrink and disappear, and finally form hair loss and baldness.
Current studies have indicated that although androgenetic alopecia is “sex inherited”, there are variables whose genetic expression is affected by gender, that is, males are “dominant” and females are mostly “recessive”. Therefore, the problem of hereditary hair loss is not a problem. only for men.
A visual inspection has been able to determine the chance of “genetic hair loss”
First of all, both men and women can inherit the gene for hair loss.
If only one parent is bald, the child will not necessarily be bald. If both parents are bald (or if the mother has a hair loss gene but shows no symptoms, that is, recessive inheritance), the son may not escape the fate of eventual baldness.
Even if the parents are not bald, the son may be bald, because it is possible that the mother carries the hair loss gene, but does not show symptoms (that is, the mother is recessive), and as a male, the son only inherits the mother’s hair loss gene, and unfortunately manifests.
When men’s and women’s hair follicles have the same sensitivity to DHT, because women have less DHT in their bodies than men, women’s symptoms and degrees will be different from men’s, and women’s symptoms are generally milder than men’s. some men.
Because hereditary hair loss is caused by genes, there is currently no cure for it in medicine, only symptomatic treatment can be given to cure it.
Currently, the drugs that have been used for a long time are the oral drug “Finasteride” (Finasteride) and the topical “Minoxidil” (Minoxidil), both of which need to be treated in the early stages of hair loss. . and gone, it’s hard to work, and both need long-term medication.
“Finasteride” is a drug prescribed by a doctor in Hong Kong. Recommended for men only. The usual dose for treating hair loss is 1mg per day for at least 3 months. Common side effects include dizziness, fatigue, and changes in sexual performance or interest (which are generally less likely to affect sexual performance), and should be avoided by family planners to avoid the risk of teratogenicity.
After stopping taking “finasteride”, the effect can be reversed within 12 months. It is recommended not to stop the drug suddenly, but to stop the drug gradually, such as taking one tablet a day, changing to half a tablet a day, or taking it once every two days, etc., etc. Take 3 to 4 months to complete the withdrawal. Before stopping the drug, if minoxidil is not used, it is recommended to use minoxidil externally.
The topical “minoxidil” is a vasodilator used to treat hair loss, which works by increasing blood flow to hair cells, thereby stimulating their growth. Males and females can use, divided into doses of 2% and 5%. The appropriate dose should be chosen according to the needs and the doctor’s recommendation. This medicine is an over-the-counter medicine in Hong Kong. Common side effects are changes to hair texture, itching, contact dermatitis and redness. If the above conditions occur, the dose and frequency can be adjusted to relieve symptoms. It must be used for a long time, and once the drug is stopped, hair loss will occur again.
If the scalp does not have enough hair, you can consider hair transplant surgery. Generally, the hair follicles are surgically removed in the “post-occipital area” of the head. Because the hair in this area is not sensitive to DHT, it is suitable to be transplanted to the area of hair loss It is still necessary to continue the medication afterwards to help maintain the effect.
Regular hair transplant surgery, the surgery is successful and the survival rate of hair transplant can reach more than 90%, which generally lasts for 10 to 20 years. However, how long it can last depends on the underlying condition of the individual’s hair.
The simplest alternative is to wear a wig.