Professor Oh Soo-yeon (left) of the Chaum Immune Enhancement Clinic and Professor Choi Sang-woon of the Clinical Gene Center
Professor Oh Su-yeon and Choi Sang-woon’s team analyzed NK cell activity by age and gender
Life Center Chaum (Director Lee Dong-mo) A team led by Professor Oh Su-yeon of the Immune Enhancement Clinic and Professor Choi Sang-woon of the Clinical Genomics Center confirmed that vitamin D deficiency and lack of exercise affect NK cell activity.
This study is meaningful in that it was the first in the world to reveal the difference in NK cell activity according to age and sex, and the effect of vitamin D and exercise on NK cell activity.
Professor Oh Su-yeon and Choi Sang-woon’s team conducted a study using ‘NK cell activity’ as an immunity index for 2,095 people who received health checkups in Chaum from 2016 to 2018.
NK cells are innate immune cells called natural killer cells that play an important role in fighting viral infections or preventing cancer. NK cell activity test is used to determine the functional state of immunity.
According to the results of this study, NK cell activity decreased with age. This phenomenon was observed only in men, and in particular, NK cell activity decreased with age from the age of 50 to 70 compared to men aged 18 to 40. In addition, it was confirmed that the activity of NK cells was low in the case of vitamin D deficiency or lack of exercise. Vitamin D deficiency had a greater effect on men, and lack of exercise had a greater effect on women and the elderly.
Professor Chaum Oh Su-yeon said, “This is the first time that vitamin D and exercise have been studied on the effects of immunity on immunity by gender and age. Because exercise is an important factor in immunity for women and the elderly, it is recommended to exercise 2-4 times a week for 1-2 hours.”
This study was published in the latest issue of the International Journal of Immunology ‘Frontiers in Immunology (impact factor: 7.561)’.
Reporter Jae-beom Kim, Donga Sports Donga [email protected] View more articles by reporter