BEIJING, Jan. 26 (Xinhua) — A study published this week in the journal Cell Discovery revealed that a group of Chinese virologists have developed a technique to help preserve vaccines Inhibiting the type of coronavirus infection (COVID-19) mRNA at normal temperatures for more than half a year
Currently, most mRNA vaccines require storage at -20°C to -70°C due to their low stability which limits their availability.
The results showed that freeze-dried lipid vaporized lipid nanoparticle (LNP) vaccines. prepared by a freeze-drying technique (lyophilization) with precise temperature control and lower residual water content It managed to maintain its physicochemical stability at 25 °C for more than 6 months, together with a strong activation of aqueous and cellular immunity in mice, rabbits or macaques
Human trials have shown that vaccination against the mutant type virus Omicron species The new form is a booster dose. It also builds strong immunity. The titer or neutralizing antibodies against the virus Omicron species many subspecies increase by at least 253 times more after this booster dose following two doses of the commercially inactive vaccine.
The researchers said the new technique overcomes the instability of mRNA vaccines. without affecting the bioactivity of the vaccine and significantly increasing their reach. especially in remote areas
(Xinhua file photo: mRNA-type COVID-19 vaccine at the 4th China International Import Expo in Shanghai, east China, November 7, 2021).
