(MENAFN – Jordan Times) A study from the University of Nottingham in the UK found that there is a link between dementia and certain anticholinergic drug classes.
As a result of these drugs – especially antidepressants, bladder antimuscarinics, antipsychotics and antiepileptic drugs – increased almost 50 percent on dementia margins, according to the observational study published Monday in JAMA's Internal Medicine magazine.
Anticholinergic drugs help to relieve muscles and relax in the Mayo Clinic. They can also be used to treat ulcers and to prevent smears. This is done by blocking neurotransmitter in the brain, acetylcholine, from entering the nervous system.
Doctors prescribe these types of drugs to treat different conditions including chronic obstructive pulmonary disease, bladder conditions, allergies, gastrointestinal disorders and symptoms of Parkinson's disease.
The risk only applies to 1,095 daily doses within a 10-year period, equivalent to an older adult taking daily anticholinergic medication for at least three years.
The study is important because it strengthens the evidence of growing evidence that shows that strong anticholinergic drugs are associated with dementia risks, & said Carol Coupland, professor of medical statistics in primary care at the University of Nottingham.
It also shows the types of anticholinergic drugs that have the strongest associations. This is important information for physicians to be aware when thinking about prescribing these drugs, 'she told CNN. This is an observational study and so no firm conclusions can be found about whether these anticholinergic drugs are causing dementia.
The study cautions people not to stop any of the medicines listed without consulting their doctors.
The researchers have not received any significant increases in the risk of dementia associated with anti-bone, skeletal muscle relaxation, gastrointestinal anti-modeling, antiarrhythmics, or antimuscarinic bronchodilators.
Approximately 47 million people worldwide were living with dementia in 2015, while in the United States, approximately 5.7 million people have dementia, according to the study.
Anticholergenic drugs include Artane, Bentyl, Oxytrol, Neosol, Symax and Vesicare but are not limited to them. A full list can be found at Mayo Clinic.
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