Covid-19 is still there. XBB.1.5 is still hot.

Thai weekly reports figures From February 19-25, 2023, the number of people infected with “COVID-19” who were sick until they arrived at the hospital was 204 people, 9 people died.

The daily number of new infections is expected to be as high as 1,458-2,024 people.

Updating the strain of the virus “COVID-19” that has spread worldwide Gerstung M from Germany noted that the current situation, XBB.1.5 and its relative XBB.1.9.1, is likely to dominate the world cases – wide

Although the BQ.1.xa BA.2.xa which used to be highly contagious is continuously decreasing.

In accordance with the previous risk assessment of the World Health Organization of XBB.1.5, “XBB.1.5” should continue to expand over the next period.

The nature of the cellular immune system After infection in a previously vaccinated person?

Koutsakos M and colleagues from Australia have answered a question that many people have been thinking about for a long time … have we been vaccinated. Unintentionally infected with COVID-19, how will our cellular immune system respond?

…It was known that “After infection” increases the immunity in the blood or the antibodies But after a few months Antibodies are reduced.

This research suggests that after infection the cellular immune system is rapidly activated by CD4 and CD8 T cells. CD4-like cells are activated as early as 1 day after the onset of illness. and increased dramatically, peaking within 5 days of illness onset

CD8, which plays a role in destroying infected cells, is also activated in response, with the amount of CD8 produced varying. and has a response time next to CD4.

When this is true…Assoc Prof Dr Teera emphasized that Paying attention to health is important for living in the current situation, being careful not to underestimate the environment to be better ventilated than in the past.

“Wearing a mask properly will greatly reduce the risk. Both from COVID-19 and PM 2.5, prevent yourself from getting infected. or not reinfected would be best”

Although the reported number of infected people in Thailand is not so much as to be alarming. However, don’t get bored with the information on this topic…

Another update found that “If infected, there will be a problem with COVID. Vaccinated people are less likely to experience Long COVID symptoms. They were also about twice as likely to have their symptoms go away than those who were not vaccinated.”

Data in this regard comes from Tran VT et al. from France. Published the results of a study in the international medical journal BMJ Medicine (28 February 2023) comparing the symptoms in a group of 910 COVID-19 patients, both in the group … “vaccinated” and “unvaccinated”

With information from different research increasing State the benefits of vaccination. As well as reducing the risk of serious illness reducing the risk of death and reducing the risk of COVID-19 If infected, it is Covid Long. Vaccination also tends to reduce symptoms. And there is a greater chance that the long covid symptoms will subside than without vaccination.

…Be careful in your life. Protect yourself regularly.

Spreading the illusion that people should be infected in order to have stronger immunity than vaccination is wrong and will cause problems in the future. For sufferers who believe that all infections are at risk of getting sick, seriously ill, dying, or having problems with COVID-19 even after being vaccinated before.

Therefore, health care and therefore protective behavior is important Especially during the epidemic…“it’s not quite quiet yet”

Late last month, the World Health Organization published a risk assessment report for the “Omicron” subtype XBB.1.5, which is a subspecies resulting from crossbreeding the virus into the BA.2 line. The report has been found in 74 countries around the world…

During XBB.1, there is a genetic change that reduces the binding of the virus to the ACE2 receptor on the cell surface. But when there was a mutation to XBB.1.5, the altered genetic location was found to be 486P.

Enhances the binding ability of the ACE2 receptor on the target cell surface. As a result, this subspecies has an outbreak that is spreading faster than before.

while avoiding that immunity It is clear that XBB.1.5 is immune resistant like XBB.1, which is considered one of the most immune resistant viruses among all omicron fires that have existed.

this immune resistance As a result, the antibodies from older vaccines are not enough to neutralize the virus. But current data suggests that Immunization with the new version, the bivalent vaccine, has been modified to immunize against Omicron BA.5, producing higher levels of antibodies than the original vaccine.

However, the level of antibody after the booster will decrease over time. But it is believed that the body’s cellular immune system will continue to work to fight the virus when it is infected. and can help reduce the risk of serious illness

Regarding severe illness from XBB.1.5, the available data suggest that its severity is similar to the previous types and that the altered genotype of XBB.1.5 is not expected to be affected by the XBB.1.5 loci The ability to worsen the illness

In summary, it is expected that “XBB.1.5” will continue to cause further expansion of the cases. because of knowledge of different performance areas mentioned above

spell protection You still have to continue to do that, do not let the lack of defects … You should maintain daily life consciously, not carelessly, protect yourself regularly. Watch out for dangerous behaviour. dangerous place Improve ventilation at home, at work, at school, where to eat and drink.

Wearing a mask correctly can greatly reduce the risk. both of COVID-19 And small, toxic PM 2.5 dust… Now around us, there are still people who are infected, adults and children, with mild illnesses, but always be aware of the long term effects like Long Covid.

“Not infected” or “Never reinfected”…is the best.