(Reuters Health) – People with type 2 diabetes are more likely to develop spinal fractures that are sometimes unclear but linked to an increased risk of future broken bones, a research review recommends.
The analysis focused on so-called vertebrate fractures, also known as compression fractures, which occur when bones weaken and close in the spine, often in the lower back. These fractures can result in injuries or osteoporosis and may have few symptoms, but may result in problems such as chronic chronic pain or reduced height.
The current study included data from 15 preliminary studies with a total of 852,702 men and women. Overall, people with type 2 diabetes were 35 per cent more likely than those who did not have vertebrate fractures, the analysis was obtained.
And people with both diabetes and vertebrate fractures were more likely than others to have broken bones elsewhere in the body.
“At present, there are no specific guidelines for assessing the risk of fracture or treatment of osteoporosis in individuals with type 2 diabetes,” wrote Fjorda Koromani from Erasmus University Medical Center in Rotterdam, the Netherlands, and colleagues. in Diabetes Care.
“Based on our findings, we recommend that people with type 2 diabetes should be systematically assessed for the presence of vertebrate fractures,” they write.
Moreover, when people with diabetes have vertebrate fractures, the study team recommends that this would be a good reason to treat osteoporosis to prevent future broken bones.
Type 2 diabetes is linked to increased risk of complications such as heart attacks and strokes, nervous damage, kidney failure, visual deterioration and premature death. People with diabetes are at greater risk of hip fracture and other broken bones.
People with diabetes still had a 94% higher risk of broken bones in the study that did not have vertebrate fractures compared to those without diabetes. And people with vertebrate fractures without diabetes had a higher risk of broken bone 73%.
When people had diabetes and vertebral fractures, they were 2.4 times more likely than broken bones.
People with diabetes and vertebrate fractures were also more likely to die prematurely than others, with the greatest risk being seen among heavier people, particularly obese people.
One of the findings is that the smaller studies included in the analysis did not examine in detail how the risk of bone fracture or premature death depended on body mass.
Another drawback is that researchers did not have data on the type of treatment people used with diabetes, which left it impossible to decide if the results were affected by diabetes medication.
However, the results suggest that vertebrate fractures may pose a health risk to people with diabetes.
“The presence of vertebrate fractures in patients with type 2 diabetes is also calling for attention to people who may be at risk of death than expected from type 2 diabetes alone,” the researchers write.
SOURCE: bit.ly/2KlvqPx Diabetes Care, online October 28, 2019.
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