Today (30 Apr. 20) Dr. Chalermchai Boonyaleephan, “Doctor Chalermchai”, Vice-President of the Senate Public Health Commission, posted a request through a blockdit application called “Hundred Eight Thousand Nine and Dr. Chalermchai said:
Vaccination 3 with Moderna vaccine following 2 doses of Astrazeneca showed a 29-33-fold increase in immunity, less resistant to BA.2 than BA.1, but able to cope with “Omicron”.
The 4th wave of Covid-19 in Thailand caused by the Omicron virus or “Omicron” since January 2022 onwards. The main viral strain has been identified from subspecies 1 (BA.1) in December 2021 to the onset of subspecies 2 (BA.2) in January 2022 and is now BA.2 strain. almost all of them make it interesting that How much will the 3rd dose booster vaccination fight the Omicron virus? Especially the BA.2 strain, which is the main strain at the moment.
There are data on the effectiveness of vaccine studies in Chiang Mai. During January to March 2022, it was found that two injections did not prevent infection. but reduced mortality by 85%.
The three injections were effective in preventing infection by 34-68% and reducing death by 98%.
interesting is And how much is the level of immunity that is up from 3 injections of vaccination is more than 2? And what are the differences between the first and second subspecies? Now there is an answer From the preliminary research study of the Faculty of Medicine, Chulalongkorn University Published in the world’s leading journal (Journal of Infectious Diseases), the blood was tested in 30 volunteers aged over 18, with a mean age of 50, who had received two doses of Astrazeneca and had never been infected. Covid came before the 3rd vaccination, Moderna, 5-7 months away from the second dose.
After that, blood was collected. To determine the level of immunity at 28 days after the 3rd dose vaccination, the level of immunity against BA.1 virus increased from 16.6 to 548 and against BA.2 strain increased from 11 to 324. Moderna’s third dose, following Astrazeneca’s two-dose vaccine, was able to induce a 29-33-fold increase in immunity against the “Omicron” virus, which was sufficient to counteract Omicron. Effectiveness against the second viral subspecies (BA.2), the current main strain. are 1.7 times less than the first subspecies, therefore it is necessary to follow up on further studies whether How long will the level of immunity for the 3rd vaccination last? which has preliminary information from some countries that Live for about 3-6 months.