“Helicobacter pylori eradication treatment prevents coronary artery disease, ‘the world’s leading cause of death'” – ​​Herald Economy

The effect of preventing coronary artery disease is remarkable in men under 65 and women over 65

From left, Professor Kim Na-yeong, Gastroenterology Specialist Kim Sang-bin, and Seoul National University Bundang Hospital Professor of Cardiology Hwang In-chang

[헤럴드경제(성남)=박정규 기자]Seoul National University Bundang Hospital Department of Gastroenterology Professor Kim Na-young’s team (Gastroenterology Specialist Kim Sang-bin and Seoul National University Bundang Hospital Cardiovascular Department Professor Hwang In-chang) found that Helicobacter pylori eradication treatment is highly effective in preventing artery disease coronary in men under 65 and in women over 65 establish the facts.

Our body’s heart beats around 100,000 times a day throughout our lives and is responsible for supplying blood throughout the body. In order to support the massive activity of the heart, the heart muscle itself also needs a lot of oxygen and nutrients.

These coronary arteries are damaged by metabolic diseases such as hyperlipidemia, diabetes, and hypertension, and when arteriosclerosis where cholesterol builds up on the walls of the blood vessels develops and the inner diameter of the blood vessels is narrowed or block significantly, can cause serious. heart disease.

When most of the coronary arteries are blocked and the heart muscle dies, it is called a ‘myocardial infarction’, and when blood flow is blocked and chest pain is felt , it is called ‘angina pectoris’. Coronary artery disease is the second leading cause of death after cancer in Korea and is known to be the most common cause of death worldwide.

Professor Kim Na-young’s team attracts attention by revealing that Helicobacter pylori eradication treatment, which represents the prevention and treatment of gastrointestinal diseases such as gastric cancer and gastric ulcer, contributes to reducing the risk of coronary artery disease.

For several years, the research team has consistently noted the fact that Helicobacter pylori eradication treatment has a positive effect on curing diabetes and hyperlipidemia, which cause various vascular diseases. In particular, it is worth noting that in this study, the preventive effect of heart disease appears in different age groups according to men and women.

This study was conducted on 7,608 patients who underwent gastroscopy at Seoul National University Bundang Hospital between 2003 and 2022.

The research team followed the cumulative incidence of coronary artery disease in 4,765 Helicobacter pylori infected patients without coronary artery disease who received eradication treatment (n = 3783) and patients who were not eradicated (n = 982). There were no differences between the two groups in terms of age, gender, alcohol consumption, smoking status, diabetes, hypertension, and aspirin intake, which allows an accurate comparison.

As a result, they found that the cumulative incidence of coronary artery disease in men and women who had Helicobacter pylori eradicated by eradication treatment was significantly reduced compared to the non-eradicated group. in women over 65, such prevention was found to be highly effective.

Regarding this difference between men and women, the research team found that female hormones (oestrogen) have the effect of strengthening the immune response to infections and dilating blood vessels, so men under 65 or women over 65 with relatively low estrogen levels can be treated with elimination, and is believed to be highly effective in preventing cardiovascular disease.

This study, following the fact that the research team proved that Helicobacter pylori eradication treatment has a positive effect on reducing the level of cholesterol or glycated hemoglobin (HbA1c), can contribute significantly to the prevention of serious cardiovascular diseases caused by these metabolic diseases have a deep meaning by explaining

Professor Kim Na-young said, “Helicobacter pylori is well known as a bacterium that causes gastrointestinal lesions such as gastric cancer and gastric ulcer. in Korea, indicated, eradication treatment needs to be actively considered if infection is confirmed,” he said.

The results of this study were recently published in the prestigious international journal ‘Helicobacter’.


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