If you drink one more cup of coffee a day, the risk of diabetes is 6% ↓ Why?

Dutch research team “C-reactive protein lowers the level of inflammation”

In particular, espresso coffee is effective in preventing diabetes.[사진=게티이미지뱅크]

A study found that coffee reduces the risk of type 2 diabetes, and the reason for this is that coffee reduces the level of C-reactive protein inflammation in the body.

A research team at Erasmus University Rotterdam Medical Center in the Netherlands found that drinking one more cup of coffee a day reduced the risk of developing type 2 diabetes by 4-6%, as a result of a large cohort study (same group).

According to a group of experts, most adults should drink 3 to 5 cups of coffee a day (with up to 400 mg of caffeine). Pregnant or breastfeeding women are advised to reduce their daily caffeine intake by 50% to 200 mg. A cup of coffee contains on average around 70 to 150 mg of caffeine.

To find out why coffee reduces the risk of developing type 2 diabetes, which is mediated by inflammatory biomarkers (biomarkers) in the body, the research team investigated the levels of inflammation and insulin resistance in regular coffee drinkers. To this end, data from the UK Biobank (145,368 registrants) and the Netherlands Rotterdam study (7111 registrants) were analysed.

I especially like espresso coffee… Adults, 3 to 5 cups a day

As a result of the study, it was found that coffee lowers the level of the inflammatory biomarker of C-reactive protein (CRP), which is elevated when the body is inflamed. Type 2 diabetes is partly an inflammatory disease. Lower levels of inflammation also reduce the risk of developing diabetes. In particular, espresso or filtered coffee drinkers were found to have a much lower risk of developing diabetes. Coffee has also been shown to reduce insulin resistance, CRP and leptin levels, and increase adiponectin levels. The hormone leptin suppresses appetite and burns a lot of calories. Adiponectin, a hormone that regulates glucose and lipid metabolism, helps break down fat and reduces inflammation.

The researchers measured the amount of extra coffee consumed based on individuals’ different levels of daily consumption, rather than on any specific criteria. The participants’ daily coffee consumption ranged from 0 to 6 cups. The first author of the study, Associate Professor Trudi Butman (Nutritional Epidemiology), said: “A study that increased coffee consumption reduced the risk of type 2 diabetes, but the underlying mechanism was unclear, so we conducted the study.” Previously, if you look at the results of the Karolinska Institute in Sweden, caffeine in coffee, green tea and chocolate reduces the risk of type 2 diabetes and reduces body fat.

The results of this study (C-reactive protein partially mediates the inverse association between coffee consumption and risk of type 2 diabetes: The UK Biobank and Rotterdam study cohorts) are in the international journal ≪Clinical Nutrition≫. The research was funded by the Coffee Science Information Institute (ISIC), a non-profit organisation.

Reporter Kim Young-seop

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