Know before vaccinating against COVID! The doctor recommends how to observe thrombosis and low platelets.
On September 21, Assoc. Prof. Dr. Nophachan Auprasert Department of Hematology Department of Internal Medicine Faculty of Medicine Chulalongkorn University revealed that at present, more than 30 million people have been vaccinated against COVID-19 in Thailand and are accelerating vaccination to build immunity for people across the country. But many people still have concerns about the safety of the COVID-19 vaccine. and adverse reactions after vaccination such as thrombosis after vaccination against COVID-19 or VITT (Vaccine-Induced Immune Thrombotic Thrombocytopenia).
Assoc. Prof. Dr. Nophachan said. Thrombosis is the leading cause of death in normal people. which coronary artery disease in the heart is clogged clogged arteries in the brain and vein thrombosis in the leg It is the top 3 most common thromboembolic events in the general population. The most common risk factors for thromboembolism in the heart and brain are several: height, age, obesity, smoking, high blood pressure, diabetes, and hyperlipidemia. and genetic factors While leg vein thrombosis is the most common venous thromboembolism. The major risk factors include old age, obesity, prolonged inactivity, cancer, estrogen (birth control pills, pregnancy), and genetic factors.
“For patients with COVID-19 The risk of thrombosis is many times higher than that of normal people. from the study meta-analysis Published in the journal Thorax in 2021, it compiles reports of 102 studies that found COVID-19 cases. Up to 15% of venous thrombosis occurs and up to 23 per cent in COVID-19 patients. admitted to the ICU while experiencing a COVID-19 patient with approximately 4% of thromboembolic arterial thrombosis; It is more severe and has a higher mortality rate than thromboembolic events in the general population,” said Assoc. Prof. Naphachan.
Assoc. Prof. Dr. Nophachan said. While the COVID-19 vaccine All of them are very safe. However, there have been reports of cerebral venous thrombosis. with thrombocytopenia after COVID-19 vaccination Adenoviral vectors in 5-30 days with thrombocytopenia less than 150,000/µL with thromboembolism. call this condition Vaccine-induced thrombocytopenia or vaccine-induced immune thrombotic thrombocytopenia (VITT).
Assoc. Prof. Dr. Nophachan said. Even though the situation is severe But it is a very rare complication. A study published in the Journal of the American College of Cardiology 2021 found that the likelihood of cerebral thrombosis after vaccination was 3.6 per 1,000,000 people, while the likelihood of atherosclerosis was 3.6 per million. Black cerebral thrombosis from being infected with COVID-19 is 207 per 1,000,000 people, which is the risk of cerebral venous thrombosis from COVID-19. This is 70-200 times greater than the risk of vaccination.
The chances of thrombosis after vaccination It was found that all types of vaccination against COVID-19 did not increase the risk of thromboembolism in both the coronary arteries. cerebral artery and veins in the legs Compared to the thromboembolic rate in the general population.
For post-vaccinated immune thromboembolic thrombocytopenia, or VITT, the likelihood of VITT is less than 1 in 100,000 vaccinated doses in the European population. However, data from India show the likelihood of VITT. There is less than 1 in 1,000,000 doses and in Thailand the chance of VITT is less than 1 in 2,000,000 doses.
“Thromboembolism after injection of the COVID-19 scene Most of them are co-occurring events. (coincidence), usually caused by congenital disease or risk factors of those who are vaccinated Where sometimes those who get vaccinated do not know that they have congenital diseases such as diabetes, high blood pressure, cancer, etc. “said Assoc. Prof. Dr. Naphachan. But it’s not a complication to worry about for getting the COVID-19 vaccine. Because the chance of encountering is very low, however, people with various congenital diseases. You should control your own disease well. Taking medications and regular follow-up checks is more likely to prevent thrombosis from your underlying disease than prevent thromboembolism from the vaccine.
Assoc. Prof. Dr. Nophachan also discussed how to observe the symptoms of thrombosis by yourself. that general symptoms that occur after vaccination such as fever, headache, body aches fingertip tea or pain in the arm on the side where the injection was given It usually goes away on its own within 48-72 hours without requiring any special treatment. Therefore, if you experience headaches, blurred vision, limb weakness, abdominal pain, nausea, vomiting, swollen legs, chest pain, unusual tiredness for more than 3 days after vaccination. or a new symptom after vaccination during 5-30 days should consult a doctor.
“Currently, the chance of dying from contracting COVID-19 is as high as 1-2 percent, which is higher than the risk of vaccinating against COVID-19. a thousand times as much The vaccination against COVID is therefore very useful for both the self in preventing infection. or reduce the severity of infection including reducing the mortality rate At the same time, it is also building immunity among the population. infection control and the burden on the country’s public health system. In addition, a study in Israel found that covid-19 infection The risk of thrombosis and serious bleeding such as cerebral hemorrhage is significantly higher than vaccination. Therefore, in addition to vaccination preventing infection with COVID-19, it also reduces the likelihood of thromboembolic events. tons after being infected with Covid-19 as well,” Assoc. Prof. Dr. Naphachan said.