Long-term obesity linked to higher dementia risk in older healthier adults

(MENAFN – Jordan Times) Healthier adults, who have been obese for years, may have a higher risk of becoming dementia than their overweight counterparts, UK research suggests.

The study team continued two groups of adults free of dementia between 65 and 74 years for up to 15 years. Among one group, who were considered healthy, 257,523 people did not smoke who did not have cancer, heart failure or multiple chronic health problems; another group of 161,927 adults, considered unhealthy, tobacco or serious chronic medical problems.

During the first decade of study, healthy people who were obese or overweight to dementia were less likely to develop healthy weight than healthy people. However, obesity was associated with a 17 per cent higher risk of dementia and was no longer heavier.

When we looked at the long-term, obesity was associated with increased risks of dementia, & The senior study author David Melzer from the University of Exeter in the UK said.

People with obesity such as diabetes and high blood pressure often have other health problems that can independently increase the risk of dementia, previous research has been found. But there are findings about the link between obesity and dementia, with some previous studies suggesting that this extra weight may be protected.

In the current study, 9,774 people were diagnosed in the healthy group. Just over half of dementia patients lost at least 2.5 kilograms in the decade before diagnosis.

Weight loss before the diagnosis of dementia could alleviate the link between obesity and cognitive decline, Melzer said by email.

Alzheimer's disease, the main cause of dementia, can develop slowly over up to 20 years before people get a diagnosis, Melzer noticed.

The same is true for damage to the arteries in the brain, which also contributes to dementia; Melzer said. This slow development of dementia makes it difficult to separate serious risk factors from the effects of the disease. # 39;

It is interesting to note that obesity was associated with the risk of lower and long term dementia for the unhealthy group in the study. 6,070 individuals developed in the unhealthy dementia group.

“In general, losing weight, being more physically active, and having blood pressure and cholesterol levels under control should make a big difference to the risk of dementia, as well as risks associated with diabetes and heart disease,” he said. Melzer.

The study was not designed to establish whether obesity could cause dementia in later years. Another limit is that researchers did not have data to examine the link between obesity and specific types of dementia as Alzheimer's disease, the author's note in Age and Aging.

In a separate study in the same journal, researchers led by Alexander Allen from the London School of Hygiene and Tropical Medicine also examined the link between overweight and dementia, and also questioned the idea that obesity is protected.

The researchers analyzed the link between excessive middle-aged belly fat and the risk of death from dementia in the next 40 years in around 19,000 male civil servants who participated in a long-term health study.

They found that weight loss was involved over 30 years, starting in middle-aged, with an increased risk of dementia in old age. However, too much fat in old age was associated with a lower risk of dementia.

While this seems to suggest that an extra weight has a protective effect, in fact, the strongest link, both weight loss over time and ultimate diagnosis of dementia, indicates the symptoms of dementia developing that helps with the weight loss, Allen writes and colleagues.

These effects can reflect changes in view or in other aspects of behavior leading to reduced energy intake, and; they notice. Thus, claims from previous studies that increase the risk of dementia may be a artefact of the effects of the reverse cause. # 39;

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Allen did not respond to requests for comments.

Regular marker weight checks that are easily measured can be provided for the risk of weakness and subsequent sensing dementia; Allen and his colleagues wrote. “It might be worth further investigation of whether this may make early intervention to improve dementia outcomes.

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Long-term obesity linked to higher dementia risk in older healthier adults

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