“Never contracted covid” may not be Super Dodgers, but there are important genes in the body.

Dr. Anan Chongkaewwatana, virologist Director of the Animal Health and Management Innovation Research Group The National Center for Genetic Engineering and Biotechnology (Bio-Technology), the National Science and Technology Development Agency (NSTDA) posted on Facebook about the case of people who “Never contract covid” can survive every season, every round, with past news and the article states that people “Never contract covid” Maybe Super Dodgers (Super Dodger) and scientists prefer it. Regarding the issue, Dr. explained. Anan as follows:

Anan said that those who “Never contract covid” with the word Super Dodgers The most obvious would be the case of people who have been exposed to HIV but have never been infected with the virus. which was a very famous phenomenon in the past Until it was discovered that HIV not only binds to CD4 on white blood cells, it can infect. There is another protein called CCR5, which opens the door for the virus to enter cells. A superdodger in the study was that people with a key mutation on the gene that produces CCR5 caused the protein to stop not be expressed on the white blood cells at all, so HIV, only binds to CD4, but has no helper to attach to the cell

Dr said. Anan that it is a very important body of information. which has led people to try to come up with the idea of ​​modifying the human gene to stop the expression of CCR5 as a treatment for infection; or AIDS patients That used to be very popular news in the industry.

but Super Dodgers The case of COVID is more difficult than the case of HIV because we know that the virus uses the ACE2 receptor protein to enter cells. It would be very difficult for someone to have a mutation, as is the case with HIV, because ACE2 has many important functions. Specifically, control of the body’s blood pressure system In other words, we lack ACE2 on the cells so we cannot lack CCR5 on the cell surface. Super Dodgers Actually using those people who “Never contract covid” Probably not, but probably someone who is infected and has never had more symptoms.

The latest research coming out as a preprint seems to say that people who Super Dodgers In the context of COVID It may be linked to a gene called HLA. This protein plays a key role in regulating the body’s immune system to fight the unactivated virus. Some people may have HLA that was triggered previously by other coronaviruses from the common cold in the past Then it can come across to prevent infection with the SARS-CoV-2 strain of corona without needing an activation time like normal people. The virus does not have time to multiply until symptoms appear in those people.

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