Those who survived each wave of coronavirus infection in the last month Scientists have discovered that the person may have a special mutated gene. who has been exposed to germs has never been infected with such a disease. But virus experts say the latest research suggests it could be down to certain genes. The one who would come to help more would be… Superdodger.
Dr. Anan Chongkaewwatana, virologist Animal Health Innovation Research and Management Group Director, National Center for Genetic Engineering and Biotechnology (Biotech) NSTDA posted via Facebook Anan Jongkaewwattana on October 1, 2022 stating that
The most obvious Superdodger is probably the case of People who have been exposed to HIV but have never been infected with the virus. which is a very famous phenomenon in the past until discovered It is important to note that HIV does not only bind to CD4 on white blood cells. can get infected There is another protein called CCR5 that opens the door. Superdodger in the study was a person with a key mutation on the CCR5-protein gene, causing this protein to enter the cell. no expression On white blood cells, HIV can only bind to CD4, but no help. to attach to the cell It is considered a very important body of information that makes people try to get ideas to modify human genes No expression of CCR5 to treat infections or AIDS patients that used to be very popular in the industry (https://www.nejm.org/doi/full/10.1056/NEJMoa0802905)
But the COVID Superdodger will be tougher than the HIV outbreak. because we know Viruses use the ACE2 receptor protein to enter cells. It would be very difficult for someone to have a mutation, as is the case with HIV, because ACE2 has many important functions. especially the control The body’s blood pressure system, we simply lack ACE2 on cells so we cannot lack CCR5 on the cell surface. So the true definition of a COVID Superdodger would be someone who has “never been infected” back probably, but he may have already been infected and never had more symptoms
The latest research coming out as a preprint seems to say that people are Superdodgers in the context of Covid. it may be linked to a gene called HLA this protein plays an important role in the control of the immune system to be ready to fight the virus Without previous stimulation, some people may also have previously stimulated HLA. Other coronavirus infections from the common cold in the past can then encounter Prevention of infection with the SARS-CoV-2 corona virus without the need to stimulate the time like normal people, which the virus does not have time to multiply. until symptoms show up in those people
https://www.medrxiv.org/content/10.1101/2021.05.13.21257065v2
#backboneMCOT
Reference and thanks for information from:
Facebook : Anan Jongkaewwattana (Dr. Anan Jongkaewwattana)
https://www.facebook.com/anan.jongkaewwattana
