Dr. Anan Chongkaewwatana, virologist Director of the Animal Health and Management Innovation Research Group National Center for Genetic Engineering and Biotechnology (Biotech), National Science and Technology Development Agency (NSTDA) Opened the research work on spike protein ofOh Micron to enter the lung cells via facebook page Anan Jongkaewwattana with the message that The latest research by the Cambridge team is a surrogate virus that uses Spike’s spiny protein.Oh MicronEntering 3D cells, the human lungs are not as good as compared to delta and traditional breeds because of the spike proteinOh Micron The cleave is not as good as the other two species, making the lung cell entry mechanism not as good. The research team believes this may be the mechanism that explainsOh Micron May not adhere to lung cells as well as other species, such as Delta and the original.
Compare with the results of the Hong Kong team. It seems to be consistent. But I have some observations and concerns: the UK team uses a surrogate virus and HK uses the real virus. deltaThe lead was significantly higher, while HK saw a difference between the original and theOh Micron whiledeltawith Oh Micron so close to each other that no statistical difference can be found This result made me think The real HK virus should have a higher rating because it is, after all, an unadulterated virus, the UK system may not be like a natural mechanism. Another point is that HK uses cells extracted directly from the human lung (ex vivo), while the UK uses lung cells that are made from stem cells and transformed into an organoid-like structure. HK’s are closer to the real thing. This is because the cells taken from the lungs have a more diverse population of cells than those produced from stem cells that are not 100% natural.
Many people who have seen the data from the UK are now comfortable that omicron can infect the lungs very little, but in my view, it is less infectious but still infectious. The HK results suggest that Omicron may infect the lungs more slowly than other strains. hours because the omicron viral load at 48 hours is also higher than Delta and the original at 24 hours. In conclusion, it is slow but still infectious. Caution is All the results we have now are in a petri dish. The in vivo data in laboratory animals has not yet been released…it may be exaggerated.
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