‘Psoriasis’ that gets worse when cold wind blows… Diabetes, joint damage, etc. [생생건강 365]
Psoriasis is often thought of as a simple skin disease caused by dry skin, but psoriasis is a chronic polygenic immunological disease.
Inflammatory substances stimulate the keratinocytes of the skin by abnormal activity of skin immune cells, causing excessive cell proliferation and skin inflammation. Mainly on the elbows, knees, buttocks, and head, red spots with clear boundaries are covered with silvery-white scales, and when rubbing with hands or taking off clothes, it itchiness and dripping like dandruff.
Psoriasis symptoms can lead to not only quality of life but also comorbidities. As psoriasis is severe, metabolic syndrome such as cardiovascular disease, high blood pressure, obesity, and diabetes is known to increase and is recognized as a systemic disease.
Also, people with psoriasis may suffer from depression or have other medical conditions such as psoriatic arthritis. Psoriatic arthritis is an inflammatory arthritis affecting the ligaments, spine and peripheral joints, and is observed in 10-30% of psoriasis patients. It causes swelling, pain, and stiffness, and once it develops, joint damage progresses, so it must be detected and treated early.
The site of occurrence is not only the spine, but also the fingers and toes and peripheral joints. In severe cases, joint deformation and movement disorders may occur.
The main cause is the inflammation that accompanies the development of psoriasis, and treatment requires reducing and controlling the inflammation. Mild symptoms of psoriatic arthritis may be treated with nonsteroidal anti-inflammatory drugs. However, if the symptoms are severe, the joints may be damaged, so immunosuppressants and biological agents may be used.
Because psoriasis is an immunological disease, recurrence cannot be completely prevented. However, the purpose of treatment is to eliminate the psoriasis lesion itself and maintain it for a long time through continuous management. Once the psoriatic lesions go away, they can stay in good shape for years.
According to the diagnosis of a dermatologist, corticosteroids, vitamin D derivatives, and moisturizers are applied directly to the wound area for treatment. In addition, phototherapy is concurrently performed. For patients with severe psoriasis who do not respond to immunosuppressants, etc., effective psoriasis management is possible using biological agents. By Kim Tae-yeol
Help : Professor Soon-Hyo Kwon of Dermatology [email protected]