On July 18, Genome Medical Center Faculty of Hospital Medicine (Hospital) Ramathibodi Mahidol University disclosed via facebook page Center for Medical Genomics to the resultsdecode genetics Test items from various hospitals in Bangkok and perimeter in the past 30 days, a total of 100 samples, indicating that
conduct genetic decodingbothgenome (Whole SARS-CoV-2 genome sequencing) andgenotype (MassARRAY Genotyping) for 2 years to check the species. and the mutation ofcorona virus 2019 with the primary objective of evaluating the efficiency and adjustments.”antiviraland “monoclonal antibody” for specific treatment (precision medicine) in accordance withOh MicronThe subspecies the patient is infected with
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from decoding genetic specimens from various hospitals in Bangkok And perimeter in the past 30 days, 100 samples found subspecies of omicron.
BA.1 2.2 percent
BA.2* 13 percent
BA.4* 54.3%
BA.5* 26.1%
BA.2.12.1 4.3%
The omicron subspecies BA.5.3.1 and BA.2.75 have not yet been found.
Omicron BA.4 and BA.5 First found in South Africa in January 2022, then it has spread around the world.
The proportion of outbreaks of BA.4 and BA.5 in each country is different.
- South Africa found BA.4>BA.5 in a ratio of 4 to 1 (Picture 1)
- Portugal found BA.5>BA.4 in a ratio of 4 to 1 (Picture 2)
- The United Kingdom found BA.4>BA.5 in a ratio of 2.3 to 1 (Figure 3).
- USA found BA.4>BA.5 in a ratio of 1 to 1 (Figure 4).
- Thailand found BA.4>BA.5 in a ratio of 4.4 to 1 (Figure 5).
From the charts 1-5, it can be seen that each country has a lower peak in the number of infected BA.4/BA.5 and BA.2.12.1 (calculated from genetic transcription) than that of infected people. BA.1/BA.2 is different from Thailand. The number of infected BA.4 is now higher than the BA.1 and BA.2 outbreaks in the past.
BA.4 The outbreaks in Thailand in the past 2 months have a relative growth advantage of 157% compared to the current outbreak (BA.5) (Figure 8).
BA.4 mutated differently from BA.5 in 7 locations (Picture 6)
BA.5 mutated differently from BA.4 in 1 position (Figure 6)
The thorn region BA.4 was mutated differently from BA.5 in 1 position (Figure 7).
There is no clinical data for BA.4 and BA.5 From around the world enough to conclude whether the two subspecies of omicron have different pathogenic virulence or “severity” (hospitalization or death).
