How much do you know about stem cells?  It is expected to increase the engraftment rate of transplanted fat and increase volume sensitivity
In any age, there is a standard of beauty. In the Renaissance in the 15th and 16th centuries, a voluminous body was followed, and in the Victorian era, corsets were used to tighten the waist for a slim waist. In the 1920s, neutral beauty was followed, and from the 1930s to the 1950s, a glamorous body became the object of envy. From the 1980s, a thin but fairly curved body shape, and in the 2000s, a voluptuous chest and hips, but a thin waist and legs became the standard of beauty.
There is one thing that does not change even in the standards of beauty that have changed over time. This is the so called ‘S line body’ with large breasts and hips and a narrow waist. The S line is a word that refers to the curvaceous beauty of a woman’s body that extends from the hip to the chest-waist, and it was the standard of beauty in most times.
◇ fat grafting, increasing the sense of volume and anticipating the effect of modifying the body shape
The wannabe women’s body of 2023 is not much different from this. To meet the needs of these women, there are various cosmetic procedures on the market.
Among the various options, ‘fat grafting’ is the fastest way to correct body shape. Fat grafting is an operation where fat is removed from areas where there is sufficient fat, that is, fat areas in the body and transferred to areas where fat is considered insufficient, such as the chest or the buttock.
Fat grafting can quickly correct body shape. Even if you work hard on a diet, you can slim down the belly, sides, inner and outer thighs, etc. by extracting fat.
◇ In order to improve the effect of fat grafting, ‘SVF’ should also be added
The biggest problem with fat grafting is how well the removed fat settles in the transplanted area. This is called the engraving rate. To increase this engraftment rate, fat cells must survive for a long time without being absorbed into the body after fat transplantation.
After fat transplantation, capillaries grow and engraftment occurs. When fat cells are placed alone, they are easily absorbed into the tissue due to the lack of function of creating new blood vessels.
If you put fat cells and SVF (Strom Vascular Fraction) together, you can overcome the limitations of fat transplantation. Since SVF contains various growth factors along with adipose-derived stem cells, it generates new blood vessels and promotes blood supply. It also plays a role in the differentiation and rebuilding of tissues, helping fat cells to survive longer.
Taking breast fat transplantation as an example, when only fat cells are transplanted, the engraftment rate is only 30-50%. This means that although the sense of volume increases significantly immediately after the treatment, the sense of volume gradually decreases as time passes.
The engraftment rate is known to reach 70-80% when fat cells and SVF are transplanted together.
In other words, if a negative pressure device is applied to the chest and SVF and fat are transplanted together, the injected fat will settle well and the volume can be maintained for a long time from the beginning .
◇ Create space for fat before fat grafting to achieve maximum effect
The first way to increase the effectiveness of SVF fat transplantation is to ensure enough space for transplantation so that the fat can live well.
If you suddenly try to put a large amount of fat under the smooth and even skin, the fat will not go in well because of the tension of the skin. Before the procedure, a negative pressure stimulus is applied to the skin to increase the space for fat to enter, and then fat is injected.
This part has also been tested in clinical studies. According to a study by Professor Dimitrios Asimakopoulos from the Department of Plastic and Reconstructive Surgery at Cambridge University School in England, the engraftment rate in fat transplantation for breast reconstruction is 45% in case of general fat transplantation, while SVF fat transplantation shows that 61% engraving rate. In addition, the skin tension was relieved, and the pain was relatively less.
In addition, it was evaluated as an advantage that a slightly higher volume can be expected compared to cases where it is not possible to put a large amount of fat in as much as there is more space to put fat in. This is because the amount of fat injected is large and the number of fat cells that can engraft well is also large. In particular, since fat transplantation can be performed twice depending on the progress after one treatment, if a large number of fat cells are well embedded in the transplanted area at the beginning, it is possible to see some effect with only one treatment.
On the other hand, SVF fat grafting is also possible for thin people. Fat is usually harvested from the abdomen or thighs and transplanted, but if you have a generally thin body and there is no place to collect fat, including the abdomen and thighs, you can proceed with surgery after increasing the amount of body fat through ex. – operation management.