“The more obese people are, the less effective vitamin D intake is”: Donga Science

Brigham and Women’s Hospital research team affiliated with Harvard Medical School

Courtesy of Getty Images Bank

There’s something not missing from the holiday gift selection survey. it’s just nutrients. In particular, vitamin D is essential for height growth in children and teenagers and is also linked to immunity, so it is also popular among the elderly, including the middle-aged.

Vitamin D is an essential nutrient involved in a variety of biological processes. It helps our body absorb minerals such as calcium and magnesium. It is also known to help prevent cancer or cardiovascular disease by stimulating the production of immune substances.

The majority of Koreans do not have vitamin D, so a high dose of vitamin D is supplemented, but a study found that the more obese people, the less effective vitamin D intake.

A research team led by Deirdre Tobias, a researcher at Brigham and Women’s Hospital affiliated with Harvard Medical School, published a study on the international journal ‘Jama Network Open’ on the 17th (local time) the higher the body mass index ( BMI). , the lower the rate of metabolism of vitamin D. .

BMI is a number obtained by dividing body weight (kg) by the square of height (m) This condition is classified as extremely obese.

The research team followed the blood data of 2,742 people who started taking vitamin D for two years and measured biomarkers such as calcium, a metabolite of vitamin D, and levels of parathyroid hormone, which helps the body use vitamin D.

As a result of the study, calcium and parathyroid hormone levels increased in people with a BMI of less than 25, but there was no significant effect of vitamin D supplementation in those with a higher BMI. The research team analyzed that the fat-soluble vitamin, vitamin D, is sequestered in adipose tissue and is not sufficiently absorbed into the body.

In addition, in the case of patients who underwent gastric resection surgery for obesity treatment, it was confirmed that the level of vitamin D in the blood increased significantly even though they did not take separate vitamin D supplements while losing a lot of weight. As part of the fat tissue in the body disappeared, the level of vitamin D in the blood naturally rose.

Researcher Tobias said, “We confirmed that the higher the BMI, the lower the effect of vitamin D supplementation.” “The concentration of vitamin D needed to prevent cancer and diabetes may be higher in obese patients.


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