According to a study by the US Centers for Disease Control and Prevention (CDC), one in 36 American 8-year-old children has an autism spectrum disorder, with a prevalence of 2.8%, a sharp increase compared to the number of cases in 2018 (2.3%) ). Autism spectrum disorder in Korea also has a prevalence of about 2%, with 1 in 50 children suffering from it, and likewise, it shows an increasing trend every year.
Autism Spectrum Disorder is a developmental disorder characterized by a delay or abnormal functioning in the development of social, language and communication skills. It is characterized by a persistent impairment in interactive social communication and interaction, such as language expression, understanding, attachment behavior, and playing with people, from early childhood, while behavioral patterns, interests, and ranges of activities are limited and repetitive.
Autism spectrum disorder is known to occur due to the interaction of genetic and environmental factors, although the cause of its onset has not been identified. There are many factors that can cause autism, from genetic mutations to stress, malnutrition, drug side effects, and viral infections. Recently, attention has been focused on the relationship between gut microbes. In the case of children with autism, there is an intestinal microbial imbalance and an abnormal increase in intestinal permeability.
In fact, according to Ariana DeGrutola’s research team at Massachusetts General Hospital and Harvard Medical School, an analysis of several studies examining autism spectrum disorders linked to bacterial imbalances found that potentially pathogenic bacteria, such as Proteobacteria and Clostridium, increased in autistic patients. In addition, it was confirmed that beneficial bacteria such as Firmicutes, Bifidobacteria, and Prevotella are reduced.
Therefore, if you suffer from autism or want to prevent it, you must use probiotics that have the effect of preventing harmful bacteria. In particular, as Bifidobacterium is reduced in patients with autism spectrum disorder, it is good to supplement Bifidobacterium strains in probiotics used to control autism.
Additionally, when Lactobacillus strains are taken together, the adhesion and growth rate of the strain can be increased. According to Ouwehand’s research team at the University of Turku, Finland, adhesion was only 18% when monocultured with Bifidobacterium lactis, but increased to 44% when co-cultured with Lactobacillus rhamnosus GG, and 45% with Lactobacillus bulgaricus improve significantly.
Currently, it is easy to find probiotics where different types of lactic acid bacteria are mixed together by checking if they are ‘metabiome’. Metabiome is a form that contains all the necessary and important beneficial bacteria as a multivitamin, and contains a number of lactic acid bacteria such as the aforementioned Bifidobacterium strain and Lactobacillus strain. In addition, it contains prebiotics, bacillus subtilis, yeast, and dead cells.
As a metabiome contains different beneficial bacteria, it diversifies the micro-organisms in the intestine and maximizes the growth and activity of beneficial bacteria to make the intestinal environment healthier. In addition, beneficial bacteria with different effects synergize with each other and act on a wide range, so effective support for autism spectrum disorders can be expected.
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