Chulalongkorn University. progressing research “vaccine cure cancer” personalised found volunteers autoimmune up-side-effects a little test prep and clinical years 66 expected another 4 years have actually used reiterated used to treat non-defense
February 10, 2565, Chulalongkorn University and the faculty of medicine, Chulalongkorn University press effect “breakthrough vaccine cancer treatment to individual innovation of hope of Thai society” by centre of excellence in the immune therapy of cancer, faculty of medicine, Chulalongkorn University and the hospital.King Chulalongkorn memorial
Assoc.Dr.The Nov.Wirot si. sport. Mr center of excellence, medical, cancer, stop.King Chulalongkorn memorial to the information that the current dosage cancer treatment guidelines 3 main ways:
- Chemotherapy is a treatment that cost is not high, medium, and may have side effects that.
- Drug targeting is a drug treatment that are specific to the mutation of cancer-effective product only in patients with mutations match with the drug symptoms, side effects, usually mild, when compared with chemotherapy and
- Immune therapy
Currently, there are both treatment dosage antibodies, and the use of cell therapy, which this guide is approved for the treatment generally good performance, not specific to the type of cancer and the majority less side effects, but side effects may include minority caused severe, sometimes
“By the research and development of cancer treatment with immune therapy-oriented development treatment in 3 ways is cell cancer therapy (CAR T-cells and NK cells) vaccine cancer treatment individually (therapeutic cancer neoantigen vaccine) and antibody-drug, anti-cancer (medicine, autoimmune, anti-cancer, immune checkpoint inhibitor)
Which immune therapy all 3 this way, with the highlight different and can be used to treat joint and combined with the treatment of cancer with other methods to enhance efficiency in the initial treatment in education, research, vaccines, cancer, personalized in kidney cancer and skin cancer types, melanoma (melanoma)or cancer of the pigment.”
Side.Tri conservation pisit Gul, head of center of excellence in systems biology, faculty of medicine, Chulalongkorn University. discussed the treatment with the vaccine cure cancer specific person that the research team had developed a vaccine for the treatment of cancer, individual since the year 2560, until the stage clinical testing phase 1 volunteers from January 2564 count as clinical testing, first in Thailand and in Southeast Asia
Vaccine production individual, this information is required, the mutation detected in the patient, so as to stimulate immunity specific to the mutation of cancer because the cancer of each patient has a mutation most different vaccine production, so have to do step 1 to create, stimulate the immune specifications, and an efficient fight against cancer
“Section provides the vaccine cure cancer specific person begins with bringing a piece of meat cancer from the patient came to decipher the genetic takes about 2 months to detect mutations found in a piece of meat, only cancer, which is not found in normal cells of the body, and bring information mutants produce a piece of proteins of cancer mutant small, with only information mutants, but not be a cause of disease without the injection of cancer cells in the body, anyhow.
By patients without hospitalization, but will have to come and get the vaccine, a number 7 times divided into 5 within the first 1 month, and spaced injection on 2 needles to stimulate to 1-2 months after vaccination myeloid antigen presenting cells will eat a piece mutant protein is produced and stimulates white blood cell type t cell to recognize the mutation of cancer more specifications”
The Nov.Tri-RAK said further preliminary 1 year ago testing the vaccine cancer treatment to individuals with volunteers, cancer patients, the number 4, which is 4(phase invasion), divided into cancer patients pigment 3 report and kidney cancer 1 report found that vaccination is safe found little side effects like pain, where vaccination, no severe side effects
And after vaccination, 3 weeks, found that after injection to 3 weeks can stimulate immunity in patients with both 4 cases improved, and clearly an immune response that are specific to parts of mutations in cancer patients.
“So, this vaccine is a vaccine cancer treatment by bringing information from a piece of meat, a cancer vaccine manufacturers non-vaccine anti-cancer and abroad, as the.Harvard’s education as well, and found that the use of vaccines, cancer treatment to individuals with dosage antibodies that enhance the immune function can optimize the treatment of elevated counts of medicine in English, count, pace international ”
The research team has detected following response to the pathology in the patient 1 report by Nov.Tri-RAK said that when evaluating the distribution of type of white blood t cells in biopsy cancer (T-cell tumor infiltration) was found to change clear
Which before the vaccination detect white blood cells located in the outer portion of the cancer primarily, and after receiving the vaccine, found that white blood cells have changes, and respond in a positive way, with distribution into a piece of meat, cancer, more present, this patient stable condition after receiving treatment with a cancer vaccine, and monitor for 9 months
The Nov.Tri RAK mentioned to target that if it is proven the effectiveness of a vaccine, which may be soon or within the next 4 years, the research team will move into clinical testing within the next start is open in the hospital.King Chulalongkorn memorial
When the research can prove the effectiveness and safety will conduct registration and at the same time a centre of excellence for immune therapy of cancer will perform research and development of antibody-drug treatment of cancer or autoimmune drug, anti-cancer parallel with, which is currently in production process in the factory and will begin testing in experimental animals this year.
Well to start clinical testing in cancer patients in the year 2566, which, if the development of vaccines, cancer treatment to a specific person and antibody-drug successfully will be able to apply the treatment, either 2-way coupled to increase efficiency in the treatment of cancer for the better and prices to help patients access to treatment.
In addition, the hospital.Chulalongkorn University.
The Thai red cross has conducted a clean room special for both the production of cells, vaccines and cancer treatment individual more in building integration of new research, together with the buildings, medical care that emphasizes care for cancer patients best combination is the center for integrated research and treatment of cancer of the king Chulalongkorn memorial hospital, Thai red cross, which is expected to be completed in February 2567
