“Vitamin D supplementation, the risk of autoimmune disease ↓”

vitamin D supplement

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(Seoul = Yonhap News) Reporter Seonggan Han = A large-scale clinical trial showed that vitamin D supplementation was effective in lowering the risk of autoimmune disease.

Autoimmune disease is a disease that occurs when the immune system misidentifies and attacks its own organs, tissues, and cells as foreign substances. Rheumatoid arthritis, multiple sclerosis, lupus, inflammatory bowel disease, type 1 diabetes, psoriasis, atopic dermatitis, celiac disease etc. belong to this.

This fact was revealed as a result of a large-scale clinical trial conducted by Karen Costenbader, a rheumatologist at Harvard University School of Medicine, Brigham and Women’s Hospital, and 25,871 men and women over the age of 50 (mean age 67). HealthDay News and News Medical Life Science reported on the 27th.

The trial participants were not vitamin D deficient at the start of the trial and had no risk factors for autoimmune disease.

The research team divided them into a 2,000 IU (international unit) vitamin D supplement group, a placebo group, and a 1 g omega-3 fatty acid group and a placebo group, and compared and analyzed the incidence of autoimmune disease over 5.3 years.

As a result, the vitamin D group showed a 22% lower incidence of autoimmune disease than the control group, and the omega-3 group had a 15% lower rate than the control group.

This effect of vitamin D supplementation began to become noticeable two years after the start of the clinical trial, and the effect became even greater after five years.

The dose of 2,000 IU of vitamin D used in clinical trials is two to three times higher than the recommended amount for adults. In general, 600 IU per day for adults under the age of 69 and 800 IU per day for adults over 70 is recommended.

The research team plans to follow up the development of autoimmune diseases in clinical trial participants over the next several years.

According to the research team, vitamin D binds to receptors on immune cells and activates various functions performed by the immune system.

As there are about 80 types of autoimmune diseases, the research team emphasized that the results of this study are very important.

The results of this study were published in the latest issue of the British Medical Journal (BMJ).

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