Small fiber neuropathy is a disease characterized by neuropathic pain and autonomic dysfunction due to damage to nerve fibers with a small diameter in the peripheral nervous system. If microfibrillar neuropathy continues, the sense of balance or body coordination may be weakened, so caution is required.
If you experience numbness, stinging, burning, or pain in your feet or toes, you may have small fibrillar neuropathy. A recently published study found that people with microfibrillar neuropathy are more likely to be obese and have an increased risk of developing heart disease.
Dr. Christopher Klein, a professor of neurology at the Mayo Clinic in the United States, and his team compared the health status of 94 patients with small fibrin neuropathy and 282 controls for an average of 6.1 years.
As a result of the study, microfibrillar neuropathy was more likely to develop when there was an underlying disease such as obesity or diabetes or hypertriglyceridemia. The average BMI (body mass index) of the patients with microfibrillary neuropathy was 30.4, which exceeded the standard of 30 for obesity. In addition, while 22% of the control group had diabetes, it was found that 51% of the patients with microfibrillary neuropathy had diabetes. In the case of triglyceride levels, the average level of the control group was 147 mg/dL, but the level of the patients with small fibrillar neuropathy was 180 mg/dL. A triglyceride level of 150 mg/dL or higher is considered high.
According to the research team, patients with small fibrillar neuropathy are at an increased risk of suffering a myocardial infarction. During the follow-up period, the proportion of the control group who suffered myocardial infarction was significantly higher (46%) compared to 27% of the control group who suffered myocardial infarction. Obesity, diabetes, and hypertriglyceridemia are known risk factors that increase the risk of myocardial infarction.
“Considering the increased risk of heart disease such as myocardial infarction in patients with small fibrillar neuropathy, more aggressive heart disease screening will be needed,” said Dr. Klein.
This study was published in the journal Neurology on the 27th (local time).
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