Clinical results, suppression of cancer cell progression by increasing ‘myokine’ in the blood after exercise
On the 11th, a study showed that exercise is effective for prostate cancer. The photo has nothing to do with the specific expression in the article. / Photo = Pixar Bay
[아시아경제 윤슬기 기자] Studies have shown that regular exercise is effective in suppressing prostate cancer.
According to Science Daily and others, on the 11th, Professor Robert Newton’s team at the Exercise Medicine Research Institute at Edith Cowan University, Australia, found that myokine, a protein secreted from muscles into the blood during exercise, causes cancer cells to multiply. Inhibits cancer and plays a key role in the fight against cancer cells.
The research team conducted a clinical trial by administering a 12-week exercise program to obese prostate cancer patients receiving androgen deprivation therapy (ADT), which reduces male hormones, and collecting blood samples before and after.
As a result of the study, it was confirmed that the rate of cancer progression was slowed by the increase of myokines in the blood after 3 months in the patients.
Professor Robert Newton, who led the research team, said, “We confirmed that cancer cell growth in the blood after exercise was significantly inhibited when blood before exercise and blood after exercise were exposed to live prostate cancer cells.”
Regarding this, researcher Jinsoo Kim, who participated as the first author of the research paper, explained, “It shows that regular exercise has created an environment that suppresses cancer in the body.”
He continued, “Myokines send signals to slow or stop the growth of cancer cells, but have no ability to kill cancer cells on their own. It can actively fight cancer cells.”
Professor Newton said, “Although ADT, a treatment for prostate cancer, is effective, it reduces lean body mass excluding body fat and increases fat mass, resulting in sarcopenic obesity, thereby improving health as well as cancer prognosis. “Exercise can be expected to have the effect of supplementing ADT,” he said.
He further speculated that this mechanism would apply to all cancers, not just prostate cancer, adding that cancer cells “may explain why even patients with metastatic advanced cancer do not die early if they are physically active.”
ADT is a treatment for prostate cancer that began in the 1940s. It is a method that inhibits the production of male hormones that can promote the proliferation of prostate cancer cells, such as testosterone and dihydrotestosterone (DHT). However, this treatment has side effects such as increasing body fat, worsening cardiovascular health, and accumulating fatigue.
The results of this study were published in the latest issue of ‘Medicine and Science in Sports and Exercise’, a journal of the American College of Sports Medicine.
Reporter Seulgi Yoon seul97@asiae.co.kr
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