55 US AI Startups That Raised $100M+ in 2025
The AI industry entered 2025 with strong momentum.
There were 49 startups that raised funding rounds worth $100 million or more in 2024, per our count at TechCrunch; three companies raised more than one “mega-round,” and seven companies raised rounds that were $1 billion in size or larger.
The industry didn’t slow down in 2025. While less companies raised rounds larger than $1 billion, four – Anthropic raised two rounds over $1 billion – significantly more companies raised multiple rounds compared to 2024, eight.
How will 2026 compare? Elon Musk’s xAI announced a $20 billion Series E round and Sam Altman’s brain computer interface startup merge Labs raised a $250 million seed round (with OpenAI as the lead investor) in the first few weeks of 2026, so signs point to another strong year. Of course, it’s still early; we’ll be watching to see if the momentum continues.
Hear are all the U.S. AI companies that raised $100 million last year:
December:
- Austin, Texas-based Mythic, which builds power-efficient compute for AI, raised a $125 million venture round that was led by DCVC. The round was announced on December 17 and included SoftBank,NEA and Linse Capital,among other investors.
- Chai Finding announced a $130 million Series B round on December 15. The round valued the company that builds AI models for biotech and drug discovery at $1.2 billion. Oak HC/FT and General Catalyst co-led the round.
- Generative media platform Fal announced its third funding round of 2025 on December 9. This December
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- Contextual AI, a generative AI startup, raised a $200 million Series B round that was announced on December 15. The round was led by Lightspeed Venture Partners and Nat Friedman.
- Glean, an AI-powered work assistant, raised a $150 million Series D round that was announced on December 12. The round was co-led by Index Ventures and Kleiner Perkins.
- healthcare AI agent startup Hippocratic AI raised a $126 million series C round that valued the company at $3.5 billion. The round was the company’s second this year, was announced on november 3, and was led by Avenir Growth.
October
- Fireworks AI, a platform that allows users to build AI applications using open source models, raised a $250 million Series C round that was valued the company at $4 billion.
- Enterprise AI startup Uniphore is valued at $2.5 billion after a $260 million Series F round that was announced on October 22. The round included snowflake Ventures,Nvidia,Databricks Ventures,and AMD,among others.
- Sesame,a voice AI company,raised a $250 million Series B round co-led by Sequoia and Spark Capital.The round was announced on October 21 and also included SignalRank as a participant.
- Cambridge, Massachusetts’s based OpenEvidence, which builds an AI chatbot for the medical field, raised its second funding round of 2025. The $200 million Series C round was announced on October 20 and valued the company at $6 billion.
- Lila Sciences, which is looking to build a science superintelligence platform, announced its second funding round of 2025 on October 14. The $350 million Series A
- AI infrastructure startup Upscale AI raised a sizable $100 million seed round that was co-led by Maverick silicon and mayfield. The round was announced on September 17 and also included StepStone Group, Stanford University, and Qualcomm Ventures, among others.
- Groq, an AI inference company, raised a $750 million Series D-3 round that valued the company at nearly $6.9 billion. The round was announced on September 17 and was led by Disruptive.
- AI training startup Invisible Technologies was valued at $2 billion after a $100 million fundraise that was announced on September 16. The raise was led by Vanara Capital with participation from Greycroft, Tallwoods Capital, and Freestyle Capital, among others.
- Cognition AI, the creator of vibe-coding agent Devin, raised a $400 million Series C round that was announced on September 8. The round was led by Founders Fund and valued the company at $10.2 billion.
- AI Infrastructure startup Baseten raised a $150 million Series D round that valued the company at $2.1 billion. The September 5 round was led by Bond with participation from CapitalG, IVP and Spark Capital, among others.
- Bret Taylor’s customer service AI agent platform Sierra raised $350 million in a round led by Greenoaks Capital. This fundraise was announced on September 4 and valued Sierra at more than $10 billion.
- You.com, a personalized AI search engine, raised a $100 million Series C round led by Cox enterprises. The round was announced on September 3 and valued the company
- Cambridge, Massachusetts-based OpenEvidence, which is building an AI-powered search tool for clinicians, raised $210 million at a $3.5 billion valuation. The Series B round was announced on July 15 and was led by Kleiner Perkins and GV.
- Harmonic, which is building a mathematical reasoning engine, raised a $100 million series B round led by Kleiner Perkins.the round was announced on July 10 and values the company at $875 million.
June
- Healthcare AI unicorn Abridge announced it raised a $300 million Series E round that values the company at $5.3 billion. The round was led by Andreessen Horowitz with Khosla Ventures participating. It was the company’s second round of 2025.
- Harvey, which builds AI tools for the legal industry, announced it raised its second $300 million round of 2025 on june 23. This latest series E round was co-led by Kleiner Perkins and Coatue and brings the company’s valuation to $5 billion.
- Healthcare AI startup Tennr announced it raised a $101 million Series C round led by IVP with participation from Lightspeed Venture Partners, GV, and andreessen Horowitz, among others. The round values the company at $605 million.
- enterprise search startup Glean continues to rake in cash. The company announced a $150 million Series F round on June 10, led by Wellington Management with participation from Sequoia, Lightspeed venture Partners, and Kleiner Perkins, among others. Glean is now valued at $7.25 billion.
- Anysphere,the AI research lab behind AI coding tool Cursor,raised a sizable $900 m
- Cambridge Massachusetts-based Insilico Medicine raised $110 million for its generative AI-powered drug discovery platform as announced on March 13. This Series E round valued the company at $1 billion and was co-led by Value Partners and Pudong Chuangtou.
- AI infrastructure company Celestial AI raised a $250 million Series C round that valued the company at $2.5 billion. The March 11 round was led by Fidelity with participation from Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others.
- Lila Sciences raised a $200 million seed round as it looks to create a science superintelligence platform. The round was led by Flagship Pioneering. The Cambridge, Massachusetts-based company also received funding from March Capital, General Catalyst, and ARK Venture Fund, among others.
- Brooklyn-based Reflection.Ai, which looks to build superintelligent autonomous systems, raised a $130 million Series A round that values the 1-year-old company at $580 million. the round was led by Lightspeed Venture Partners and CRV.
- AI coding startup Turing closed a Series E round on March 7 that valued the startup, which partners with LLM companies, at $2.2 billion. the $111 million round was led by Khazanah Nasional with participation from WestBridge Capital, Gaingels, and Sozo Ventures, among others.
- Shield AI, an AI defense tech startup, raised $240 million in a Series F round that close
Abridge Secures Funding and TechCrunch Disrupt 2026 Declaration
This report details recent funding secured by Abridge and data regarding the TechCrunch Disrupt event scheduled for October 13-15, 2026.
Abridge: AI-Powered Meeting Intelligence
Abridge is a company developing AI-powered tools designed to record, transcribe, and summarize meetings and conversations. Abridge focuses on applications within healthcare,legal,and other professional fields.
In December 2023, Abridge raised $20 million in Series B funding led by Lightspeed Venture Partners, with participation from existing investors including Sequoia Capital and Hummer Capital. TechCrunch reported on this funding round, highlighting the company’s growth and expansion plans.
The company was founded in pittsburgh, Pennsylvania, but has as expanded its operations. Crunchbase confirms the founding location.
TechCrunch Disrupt 2026
TechCrunch disrupt is an annual technology conference focused on startups, venture capital, and emerging technologies. TechCrunch Disrupt provides a platform for showcasing new companies, networking with investors, and discussing industry trends.
The 2026 event is scheduled to take place in San Francisco, California, from October 13-15, 2026. TechCrunch Disrupt 2026 is expected to feature a startup competition, keynote speakers, and various workshops and panels.
Previous TechCrunch Disrupt events have seen significant announcements and funding rounds for participating startups. For example, in 2023, over $100 million in funding was announced during the event.TechCrunch reported on the funding activity at the 2023 event.
- lightspeed Venture Partners: Lightspeed Venture Partners is a venture capital firm that led Abridge’s Series B funding round.
- Sequoia Capital: Sequoia Capital is another investor in Abridge.
- TechCrunch: TechCrunch is a leading technology news website and the organizer of TechCrunch Disrupt.
- San Francisco, California: The location of the 2026 TechCrunch Disrupt event.
Updated as of January 19, 2024, to reflect the latest available information. No breaking news or contradictory information was found regarding Abridge’s funding or the TechCrunch Disrupt 2026 schedule.