Vitamin D & Cell Aging: How It Slows Telomere Shortening
Data Extracted from the Text:
Here’s a breakdown of the information provided, categorized for clarity:
1. Research Citations (Related to Vitamin D & Arthritis):
* 8 Georgescu B et al.(2020): A systematic review investigating the current evidence and clinical implications of vitamin D levels in pain and functional management of knee osteoarthritis. (Published in Biomedical Reports, 2020; 13(4)).
* 10 Turck D et al. (2023): A scientific opinion on the tolerable upper intake level for vitamin D, including a conversion factor for calcidiol monohydrate. (Published in EFSA Journal, 2023; 21(8):8145).
2. Product Information: Dekristol® (Vitamin D3)
* Brand Name: Dekristol® (Umbrella brand,includes NVI-KT from Insight Health)
* Active Ingredient: Colecalciferol (Vitamin D3)
* Available Forms & Strengths:
* Tablets: 400 IU,500 IU,1,000 IU (10 micrograms,12.5 micrograms, 25 micrograms colecalciferol respectively)
* Drops: 20,000 IU/ml
* Inactive Ingredients (Tablets): Lactose 1H2Oh, microcrystalline cellulose, corn starch, Strength[hydrogen-2-(oct-1-en-1-yl)butandioat]-Sodium salt, carboxymethyl starch sodium (type A) (Ph. Eur.), sucrose, highly dispersed silicon dioxide, magnesium stearate (Ph. Eur.), sodium ascorbate, medium chain triglycerides, all-rac-alpha-tocopherol.
* Inactive Ingredients (Drops): Medium-chain triglycerides,butylhydroxytoluene (Ph. Eur.).
3. Indications (What Dekristol® is used for):
* Tablets:
* Prevention of rickets and osteomalacia in children, youth, and adults.
* Prevention of vitamin D deficiency in children, youth, and adults with recognizable risk.
* Supportive treatment of osteoporosis in adults.
* Dekristol 400 IU additionally: Prevention of rickets in premature babies.
* Drops:
* Prevention of diet-related rickets in infants and young children, newborns, and premature babies.
* Prevention of vitamin D deficiency in adults, youth, and children with known risk.
* Treatment of vitamin D deficiency in adults, youth, and children.
* Additional therapy for osteoporosis in adults with vitamin D deficiency or risk of deficiency.
4. Contraindications (When not to use Dekristol®):
* Hypersensitivity to any of the components.
* Hypercalcemia (high calcium levels).
* Hypercalciuria (high calcium in urine).
* Hypervitaminosis D (vitamin D overdose).
* Nephrocalcinosis (calcium deposits in kidneys).
* Nephrolithiasis (kidney stones).
* Severely impaired kidney function.
5. Side Effects:
* Hypersensitivity reactions.
* Hypercalcemia.
* Hypercalciuria.
* Constipation.
* Flatulence.
* Nausea.
* Abdominal pain.
* Diarrhea.
* Pruritus (itching).
* Rash.
* Urticaria (hives).
6. Warnings/Special Considerations:
* Tablets: Contain lactose and sucrose.
* Drops (20,000 IU/ml): Requires a prescription.
Disclaimer: I am an AI chatbot and cannot provide medical advice. This information is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.