Actualités de l’Urgence – APM / Société Française de Médecine d’Urgence
avian Flu Threat Grows: Experts Call for Urgent Surveillance
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washington, D.C. – As the highly pathogenic avian influenza A(H5N1) virus continues to spread across the U.S.,top infectious disease experts are sounding the alarm,calling for increased surveillance and research to prevent a potential human pandemic.In an editorial published Tuesday in the New England Journal of Medicine, dr. Jeanne Marrazzo, director of the National Institute of Allergy and Infectious Diseases (NIAID), and Dr. Michael Ison, chief of the division of respiratory diseases, highlight the growing threat posed by the virus.
First detected in 1997, the virus has spread rapidly through migratory birds, leading to deadly outbreaks in poultry worldwide. in 2021, the virus jumped to mammals, infecting cows in Texas and now affecting 16 states. This increased contact between humans and infected animals raises concerns about the potential for human-to-human transmission.”We need to be proactive,” Dr. Marrazzo emphasized. “Enhanced surveillance of emerging mutations and a thorough evaluation of the risk of human-to-human transmission are crucial.”
The NIAID experts point to a recent case in Canada, where a young woman was infected with the virus. Genetic sequencing revealed three mutations in the virus isolated from the patient, perhaps linked to increased virulence and adaptation to human cells. It remains unclear if these mutations were present in the original virus or emerged during the patient’s illness.
This case underscores the urgent need for more comprehensive data collection. Currently, genomic sequencing data from animals often lacks crucial facts about the location and time of sample collection, hindering researchers’ ability to track the virus’s spread and identify potentially hazardous mutations.
Beyond surveillance, the NIAID experts advocate for a multi-pronged approach to combat the avian flu threat. This includes:
Strengthened collaboration: Fostering close partnerships between human and veterinary medical researchers,public health officials,and agricultural workers is essential for effective response and prevention.
Advancement of countermeasures: Continued research and testing of vaccines and antiviral drugs are critical to prepare for a potential pandemic.
“Fortunately, current vaccine candidates neutralize circulating strains in laboratory settings, and these strains remain susceptible to existing antiviral medications,” the NIAID experts noted.
* Public health measures: Promoting awareness about the risks associated with contact with birds and emphasizing the importance of personal protective equipment in workplaces where exposure is possible are crucial steps in preventing further spread.
The avian flu threat is a serious and evolving situation. By prioritizing surveillance, research, and public health measures, the U.S. can work to mitigate the risk and protect its citizens.
bird Flu Cases Rise in U.S., Sparking Concerns
Health officials are monitoring a rise in human cases of avian influenza, also known as bird flu, across the United States.
The Centers for Disease Control and Prevention (CDC) reported 46 cases of H5N1 avian influenza in humans between March and October 2024. While the CDC maintains that the risk to the general public remains low, the increase in cases has prompted calls for heightened vigilance.
Most of the infected individuals (45) had direct contact with infected poultry or cattle. the median age of those infected was 34, and all cases were mild, with no hospitalizations or deaths reported. Symptoms primarily included conjunctivitis, fever, and mild respiratory issues.
The CDC emphasized the importance of understanding the extent of exposure, infection, viral evolution, and transmission to effectively protect communities.
“We need to strike a balance between increased awareness and maintaining normal daily activities,” the CDC stated. “Without a clearer understanding of these factors, we won’t be able to adequately protect our communities.”
The rise in cases comes as the U.S. continues to grapple with a widespread outbreak of avian influenza in poultry.
Experts urge the public to practice good hygiene, including frequent handwashing, and to avoid contact with sick or dead birds.
[Image: A photo of a person wearing protective gear while handling chickens.]
While the risk to the general public remains low, health officials are closely monitoring the situation and will provide updates as they become available.
Avian Flu Threat Grows: Experts Call for Urgent Surveillance
Washington, D.C. – As the highly pathogenic avian influenza A(H5N1) virus continues to spread across the U.S., top infectious disease experts are sounding the alarm, calling for increased surveillance and research to prevent a potential human pandemic.

In an editorial published Tuesday in the New England Journal of medicine, Dr. Jeanne Marrazzo, director of the National Institute of Allergy and Infectious Diseases (NIAID), and Dr.Michael Ison, chief of the division of respiratory diseases, highlight the growing threat posed by the virus.
A Spreading Threat
First detected in 1997, the virus has spread rapidly through migratory birds, leading to deadly outbreaks in poultry worldwide. In 2021, the virus jumped to mammals, infecting cows in texas and now affecting 16 states. this increased contact between humans and infected animals raises concerns about the potential for human-to-human transmission.
“We need to be proactive,” Dr. Marrazzo emphasized in an exclusive interview with NewDirectory3.com. “Enhanced surveillance of emerging mutations and a thorough evaluation of the risk of human-to-human transmission are crucial.”
New Mutations Raise Concerns
The NIAID experts point to a recent case in Canada, where a young woman was infected with the virus. Genetic sequencing revealed three mutations in the virus isolated from the patient, perhaps linked to increased virulence.
“This case underscores the urgent need for vigilance,” Dr. Ison stated. “We need to understand how these mutations might affect transmissibility and severity in humans.”
Call to Action
Drs. Marrazzo and Ison urge increased funding for avian influenza research, improved surveillance systems to track the spread of the virus, and the development of antiviral drugs and vaccines to protect humans from a potential pandemic.
They emphasize the importance of a coordinated global effort to combat this growing threat. “This is not just a U.S. problem,” Dr. Marrazzo said.”It’s a global health security issue that requires international collaboration.”
