Ancient Plant Holds Key to Reversing Hair Graying
- Teh most common type of hair loss, "androgenetic alopecia" (also known as male-pattern baldness), affects millions of people worldwide.
- Even though this condition is frequently enough associated with aging, it is indeed increasingly appearing at younger ages and is seen in both men and women.
- The two most commonly used drugs are treatments with the active ingredients "finasteride" and "minoxidil". Minoxidil stimulates hair follicle cells by converting to its active form in the...
Teh most common type of hair loss, “androgenetic alopecia” (also known as male-pattern baldness), affects millions of people worldwide.
Even though this condition is frequently enough associated with aging, it is indeed increasingly appearing at younger ages and is seen in both men and women. The condition, which manifests with symptoms such as recession of the hairline at the temples, thinning in the crown and forehead areas, oiliness of the scalp, dandruff, itching, and inflammation of the follicles, can lead to noticeable baldness if not intervened early.
Treatment options are limited. The two most commonly used drugs are treatments with the active ingredients “finasteride” and “minoxidil”. Minoxidil stimulates hair follicle cells by converting to its active form in the scalp; finasteride prevents testosterone from converting to dihydrotestosterone (DHT), which shrinks hair follicles.
However, the need for treatments that are free of side effects and more effective continues.
THE REDISCOVERY OF AN ANCIENT PLANT
A new review published in the scientific journal Journal of Holistic Integrative Pharmacy points to a remarkable candidate: Polygonum multiflorum. known as “He Shou Wu” in traditional Chinese medicine, this root plant has been used for over a thousand years.Described in ancient texts as a plant that “darkens hair and nourishes essence,” He Shou wu has been shown to have biological effects that support these claims through modern scientific research.
The study’s lead author, Bixian Han, said, “We combined ancient wisdom with modern science. The effects described in texts since the Tang Dynasty align with what I know today about hair biology.”
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Notable Disclaimer: I am an AI and cannot provide medical advice. This information is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.
He Shou Wu (Polygonum multiflorum): Safety and Efficacy in Hair Loss Treatment
Table of Contents
He Shou Wu, also known as Polygonum multiflorum, is a traditional Chinese medicine herb increasingly used in hair loss treatments, but its safety and efficacy require careful consideration. As of January 28, 2026, research continues to explore its potential benefits and risks.
What is He Shou Wu?
He Shou Wu is a climbing vine native to China, Japan, Korea, and Vietnam.The root is the part traditionally used in medicine. The National Center for Biotechnology Information (NCBI) details its historical use in traditional Chinese medicine for various ailments, including hair loss, constipation, and muscle pain.it’s believed to nourish the liver and kidneys, according to Traditional Chinese Medicine (TCM) principles.
Safety Concerns and Liver Toxicity
While traditionally considered safe when processed correctly, He Shou Wu has been linked to instances of liver damage.The U.S. Food and Drug Administration (FDA) has issued warnings about dietary supplements containing Polygonum multiflorum due to reports of liver injury. The primary concern stems from the presence of anthraquinones, naturally occurring compounds that can be hepatotoxic (toxic to the liver).
* Mechanism of Toxicity: Anthraquinones can cause oxidative stress and inflammation in the liver, leading to cell damage. Research published in Drug Safety highlights the potential for anthraquinone-induced liver injury.
* reported Cases: The FDA has received reports of liver damage, including jaundice and elevated liver enzymes, in individuals using supplements containing He Shou Wu. FDA Safety Alerts provide details on these cases.
* Processing Matters: proper processing methods, including steaming and fermentation, are crucial to reduce the levels of perhaps harmful anthraquinones. Though, quality control in supplement manufacturing can be inconsistent.
Efficacy in Hair Loss Treatment
The evidence supporting He Shou Wu’s effectiveness in treating hair loss is currently limited and requires further examination.
* traditional Use: Historically, it has been used to address hair graying and hair loss related to kidney deficiency in TCM.
* Limited Clinical Trials: A review in Frontiers in Pharmacology indicates that while some in vitro and animal studies suggest potential benefits for hair growth, robust, large-scale human clinical trials are lacking.These studies suggest it may promote hair follicle growth and increase dermal papilla cell proliferation.
* Potential Mechanisms: proposed mechanisms of action include antioxidant effects, stimulation of hair follicle cells, and modulation of hormone levels.
* Ongoing Research: As of late 2025/early 2026, several research groups are conducting studies to evaluate the efficacy and safety of standardized He shou Wu extracts for androgenetic alopecia (male/female pattern baldness). Results are pending.
Regulation and Quality Control
The regulation of He Shou Wu supplements varies substantially by country.
* United States: In the US, He Shou wu is sold as a dietary supplement, which is subject to less stringent regulations than pharmaceuticals. The Federal Trade Commission (FTC) provides guidance on marketing dietary supplements.
* China: In China, He shou Wu is used in both traditional medicine formulations and approved cosmetic products. The National Medical products Administration (NMPA) regulates the production and sale of these products.
* Quality concerns: Due to inconsistent manufacturing practices, the quality and purity of He Shou Wu supplements can vary widely. Third-party testing for contaminants and accurate ingredient labeling is recommended. The United States Pharmacopeia (USP) offers a verification program for dietary supplements.
Recommendations
* Consult a Healthcare Professional: Before using He Shou Wu, especially if you have liver problems or are taking other medications, consult with a qualified healthcare provider.
* Source Carefully: Choose supplements from reputable manufacturers that adhere to good manufacturing practices (GMP