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Beyond Conventional Treatments: Unlocking the Power of Replacement Therapy for Atopic Dermatitis

Beyond Conventional Treatments: Unlocking the Power of Replacement Therapy for Atopic Dermatitis

September 16, 2024 Catherine Williams - Chief Editor Health

Atopic‍ Dermatitis: Breaking​ Down Barriers to Effective Treatment

Getty Images‌ Bank

Atopic dermatitis is a chronic skin condition that significantly impairs the quality of life of patients due ⁢to severe itching. Experts emphasize the ​importance of selecting treatments based on individual symptoms, particularly for patients with severe cases.

The Atopic Dermatitis‍ Association is‍ hosting an event on the 21st to commemorate World Atopic Dermatitis Day, with the theme “Atopic Dermatitis Day, Healing and Hope Together.” This event aims to explore⁣ ways to improve treatment options,⁤ including the possibility ‍of cross-medication.

Park‌ Jo-eun, head ​of the Atopic Dermatitis Association, highlights the‍ need for personalized treatment approaches. “You can’t⁣ know what the⁤ effects‌ or side effects of a treatment will be until you ⁢try it yourself,” he says. “Many​ patients ​have used treatments with high expectations, only ‍to be disappointed by the lack of effects or side effects.”

Atopic dermatitis is often underestimated due to its non-life-threatening nature, but it requires active treatment to improve the quality of ⁢life ⁢of patients ⁢and their guardians. In severe cases, it can lead to various physical and mental illnesses, such as sleep⁢ disorders and ⁣anxiety.

Treatment strategies should be selected based on a comprehensive evaluation of factors such ⁢as the ⁤patient’s age, extent of​ the lesion, and severity. Since there are no clear research​ results on biomarkers, which ⁤predict patient responses to specific treatments, treatment approaches are currently based ⁣on clinical characteristics.

Treatment options for moderate‍ to severe atopic dermatitis include immunomodulators, such as topical steroids, topical calcineurin ⁤inhibitors, and ​antihistamines. Biological​ agents and⁣ JAK inhibitors have also been ​introduced, ⁤offering more diverse treatment methods.

JAK inhibitors, such as Upadacitinib (Rinvoq), Olumiant (Olumiant), and Abrocitinib (Sivinco), are known ​for ‍their⁤ fast-acting and ‍powerful effects. Abrocitinib, the most recently​ launched, is administered ⁢orally once a day, making‌ it more⁣ convenient than injectable treatments.

However, the current reimbursement system does not allow for the replacement of JAK inhibitors and​ biological agents, making it ‍difficult for patients to access alternative treatments. Experts emphasize the need for a more flexible reimbursement system to accommodate personalized‌ treatment approaches.

Jang Yong-hyeon,‍ insurance director of the Korean Dermatological Association, stresses the importance of personalized treatment. “Atopic dermatitis is a disease‍ that requires personalized treatment depending on the patient’s condition,” he says.⁤ “One drug does not have the same effect on​ all⁤ patients. When patients ‌show insufficient responses, other good treatments should be ⁣available.”

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