Bills vs. Broncos Prediction: Odds & 2026 NFL Divisional Round Picks

The divisional round of the 2026 NFL⁣ playoffs⁣ kicks off with‍ the Denver Broncos hosting the Buffalo Bills on ⁤Saturday. The Broncos (14-3)⁢ tied for the league’s best record, won⁣ back-to-back games ⁣to close the regular season and earned a bye as the AFC’s No.1 seed. The Bills (12-5) have won six of their last seven‍ contests, including a 27-24 road victory over⁤ Jacksonville in‍ Sunday’s wild-card matchup.‍ Buffalo safety Jordan⁤ Poyer (hamstring) has been⁤ ruled out, while defensive ‍lineman Ed Oliver (bicep) and receiver Curtis Samuel (elbow) are among the players listed as questionable.

Kickoff is at 4:30 p.m. ET from Empower Field at Mile High in Denver, ⁣where the Broncos are 8-1 this season. The ⁤latest Broncos vs. Bills odds from DraftKings Sportsbook list Denver as a 1.5-point favorite, while⁤ the over/under is 45.5. Before making any Bills vs. Broncos picks, check out the NFL predictions from the SportsLine Projection model.

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The model, wich simulates every NFL ⁢game ‍10,000 times, is up well over $7,000 for $100 players ‍on⁢ top-rated NFL ⁤picks since it’s⁤ inception. The model⁢ enters the divisional round of the 2026⁣ NFL playoffs on a⁢ 53-37 run on top-rated⁤ picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen ⁢strong returns.

Now, ⁢the‍ model has set its sights on See which ‍team to back at SportsLine.

Why the broncos can cover

This⁤ will be Buffalo’s eight divisional road game as the 1970 merger, and the Bills have covered just once over that span. One also can’t discount Denver coming off a bye, as the Broncos are 3-1-1 ATS ⁤over their last five with a rest advantage,‍ while the Bills are ⁢1-4 ATS this season when having less rest than their opponents. Denver possesses a ferocious pass rush ⁢as its 68 sacks are⁣ the fifth-most in NFL history, and the⁣ Bills have struggled when Josh Allen ⁤ is under ⁢attack. ‍The Broncos average four sacks per game, and⁢ Buffalo has lost six straight games, including being 0-3 this season, when Allen is sacked at least four times.‍ Additionally, Sean Payton and company can exploit Buffalo’s porous run defense as just four teams allowed more yards on the ground than Buffalo this season. See which team to back at SportsLine.

How to make Bills vs. Broncos ⁢ picks

SportsLine’s model has simulated Broncos vs. Bills 10,000 times and is going Over on the total, projecting 47 combined points.⁣ It also says one side of the spread hits in more than 50% of simulations. You can only get the pick ⁤at SportsLine.

so who ‍wins Bills vs. Broncos, and which side of the spread hits ⁣more than 50% of the time? Visit SportsLine now to see which side of the Broncos vs. Bills spread to jump on,