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Brazilian Study Highlights Anti-Inflammatory Potential of Joseph’s Coat plant
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Research from Brazilian universities suggests the Alternanthera littoralis plant, known as Joseph’s Coat, shows promise in treating inflammation, pain, and arthritis, but further testing is needed before clinical use.
Published December 22, 2023, and reviewed december 22, 2025, at 12:01:02 PST.
What is joseph’s Coat?
Joseph’s Coat (Alternanthera littoralis) is a plant native to the coastal regions of brazil. It’s characterized by its vibrant, multicolored leaves - typically shades of red, yellow, and green – and has a history of use in conventional Brazilian medicine. Traditionally, it has been used to address a variety of ailments, including inflammation and pain. Research published in 2023 details the plant’s phytochemical composition and traditional uses.

key Findings of the Brazilian Research
A collaborative research team from the federal University of Grande Dourados (UFGD), the State University of Campinas (UNICAMP), and São Paulo State University (UNESP) conducted a study demonstrating the plant’s potential medicinal benefits. According to the research, extracts from Joseph’s Coat exhibited significant anti-inflammatory properties, pain-relieving effects, and protective capabilities against arthritis. These findings, as reported by Arena and colleagues, strengthen the scientific basis for the plant’s traditional uses.
The study also indicated a favorable safety profile at therapeutic doses, which is a crucial step towards potential human applications. However, researchers emphasize that the extract is not yet ready for clinical use.
Safety and Efficacy Considerations
While promising,the research team cautions that further investigation is essential. Specifically, they highlight the need for:
- Additional toxicological testing to comprehensively assess safety.
- Human clinical trials to confirm effectiveness and identify optimal dosages.
- Standardized readiness methods to ensure consistent quality and potency of the extract.
- Regulatory approval from relevant health authorities before any therapeutic use can be considered.
Funding and Collaborative Research
This research is part of a broader,ongoing investigation led by UFGD,UNESP,and UNICAMP,aimed at scientifically validating Brazilian biodiversity and traditional knowledge.The project emphasizes a rigorous scientific approach to promote the safe and rational use of natural products.
The research was financially supported by the São Paulo Research Foundation (FAPESP) through the following grants: 06/06079-4, 09/05992-6, 15/03726-8, 16/06407-3, 17/19523-4, and 21/09693-5. FAPESP is a prominent funding agency supporting research in
