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Cancer Tricks Immune System with Hormone

September 14, 2025 Jennifer Chen Health
News Context
At a glance
  • For many of us, the word "cancer" conjures images of ⁤relentless battles ⁣- both within ⁢the body and‍ in the lab.
  • Imagine your immune⁣ system as a highly trained army,with T-cells as its elite soldiers,ready to target and destroy invaders like cancer cells.
Original source: earth.com

Unlocking Cancer‘s Secrets: How a⁣ “Hormone” Shields Tumors ⁣from Your Immune System

For many of us, the word “cancer” conjures images of ⁤relentless battles ⁣- both within ⁢the body and‍ in the lab. But‍ what if the enemy was using our own defenses against us? A groundbreaking study from UT Southwestern medical Center, led by Dr. Cheng Cheng “Alec” Zhang,reveals a cunning tactic some cancers employ: hijacking a natural hormone to⁢ suppress ⁣the immune system. This discovery not only sheds light on⁣ why certain cancer treatments work for some but not⁢ others, but also points towards exciting new avenues for therapy.

Imagine your immune⁣ system as a highly trained army,with T-cells as its elite soldiers,ready to target and destroy invaders like cancer cells. Now, imagine a signal that tells those soldiers to stand down, allowing the enemy to advance. That’s essentially what’s happening with Secretogranin 2 (SCG2), a hormone-like substance,‍ in certain cancers.

The SCG2 ⁢Connection: A new Target for Treatment

Dr. Zhang’s ‍team discovered that SCG2 acts as

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