Charcot-Marie-Tooth Disease: Symptoms, Causes & Isabelle Tate’s Death
Here’s a breakdown of the information provided in the text, focusing on Charcot-Marie-tooth disease (CMT):
What is Charcot-Marie-Tooth Disease?
* Also known as: hereditary motor and sensory neuropathy.
* Type of disease: an inherited nerve disease – one of the most common types.
* Symptoms:
* Muscle shrinkage and weakness (over time)
* Difficulty walking
* Loss of feeling in legs and feet
* High foot arches
* Hammertoes
* inability to run
* Clumsiness
* Difficulty lifting the foot at the ankle
* Prognosis: Generally not fatal. Most people live a normal lifespan and remain active. Rarely, it can affect breathing muscles.
* Origin of the name: named after Jean Martin Charcot and Pierre Marie (Paris) and Howard Henry Tooth (Cambridge, England) who described it in 1886.
Isabelle Tate and CMT
* Actress Isabelle Tate was diagnosed with CMT at age 13.
* She shared in a 2022 Instagram post that the disease had “really progressed” and she was beginning to use a wheelchair at times.
* She described the difficulty of accepting help and surrendering to the disease’s progression.
Sources:
* The Mayo Clinic
* Cedars Sinai
* American Academy of Orthopaedic Surgeons
* Instagram (for Isabelle Tate’s post)