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naegleria fowleri and the Growing Threat of Waterborne Amoebae
Table of Contents
This report details the risks associated with Naegleria fowleri, often called the “brain-eating amoeba,” and the broader challenges of controlling amoebae and associated pathogens in water systems. Information is based on independently verified sources as of January 26, 2026.
Naegleria fowleri Infection
Naegleria fowleri is a thermophilic amoeba that causes primary amebic meningoencephalitis (PAM), a rare and almost always fatal infection of the brain. PAM occurs when contaminated water enters the nose,allowing the amoeba to travel to the brain along the olfactory nerve.
The Centers for Disease Control and Prevention (CDC) reports that infections are rare in the United States, with 154 infections identified from 1962 to 2022. CDC Epidemiology Data shows most infections occur in southern states, and are linked to recreational water exposure in warm freshwater, such as lakes, rivers, and hot springs. The CDC states that while the number of cases is small, the fatality rate is over 97%.
Recent cases have expanded the geographic range of concern. In 2023, cases were reported in Nebraska and Kansas, states previously considered low-risk.NBC News Report on 2023 Cases
Challenges in Amoebae Control and Disinfection
Amoebae, including Naegleria fowleri, are arduous to control due to their resilience to common disinfection methods and environmental conditions. They can survive high temperatures and tolerate disinfectants like chlorine, allowing them to persist in water distribution systems.
research published in *Environmental science & Technology* highlights the ability of amoebae to form cysts, which are highly resistant to disinfection.ACS Publication on Amoebal Cysts This allows them to survive even in treated water systems.Furthermore, amoebae can harbor other pathogens, providing a protective niche against disinfection processes.
For example, *Legionella*, the bacteria that causes Legionnaires’ disease, has been shown to proliferate within amoebae, increasing its resistance to chlorine and other disinfectants. National Institutes of Health Study on Legionella and Amoebae This “Trojan horse” effect complicates water safety management.
Climate Change and the Spread of Amoebae
Rising global temperatures are exacerbating the problem by expanding the geographic range of thermophilic amoebae like Naegleria fowleri. Warmer water temperatures create more favorable conditions for their growth and survival,allowing them to spread into regions where they were previously uncommon.
The World Health Association (WHO) has identified climate change as a significant driver of infectious disease emergence and spread. WHO Climate Change and Health Report Increased frequency and intensity of heatwaves contribute to warmer water temperatures, increasing the risk of Naegleria fowleri infections.
The CDC reports that the average water temperature in recreational areas has increased over the past several decades, correlating with the observed expansion of Naegleria fowleri’s geographic range. CDC FAQs on Naegleria fow
