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Europe's Best Stock: 1,400% Gain This Year - News Directory 3

Europe’s Best Stock: 1,400% Gain This Year

December 18, 2025 Victoria Sterling Business
News Context
At a glance
  • French biotech company Abivax is the best-performing stock in the stoxx 600 this year, with a significant lead over the others, according to CNBC.
  • Shares are up 1,441% sence the start of this year, a staggering figure even for a clinical-stage biotech company known for its price volatility and high risk.
  • Abivax's strong rally began with a ‍510% rise on July 23, a day after the company reported ‍data from a late-stage trial of its lead product obefazimod, an...
Original source: investor.bg

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abivax Stock Soars: A ⁢Deep Dive into the Biotech’s 1,441% ‍rise



Abivax Stock Soars: A Deep Dive into the Biotech’s 1,441% Rise

Table of Contents

  • Abivax Stock Soars: A Deep Dive into the Biotech’s 1,441% Rise
    • 2026 ⁢is Full of Catalysts
      • At a Glance
      • Editor’s Analysis

French biotech company Abivax is the best-performing stock in the stoxx 600 this year, with a significant lead over the others, according to CNBC.

Shares are up 1,441% sence the start of this year, a staggering figure even for a clinical-stage biotech company known for its price volatility and high risk. By⁤ comparison, the next best-performing stock is British⁣ miner⁤ Fresnillo, which is up 373% year-to-date.

Abivax’s strong rally began with a ‍510% rise on July 23, a day after the company reported ‍data from a late-stage trial of its lead product obefazimod, an ulcerative colitis drug.

Since then, the stock has continued to⁢ rise on investor optimism about the⁢ company’s product line, as well‍ as⁢ unconfirmed rumors of a takeover bid by a larger competitor.

“We’re constantly in talks with the big pharma companies,” CEO Marc de Garridel told CNBC ⁤on Tuesday, but stressed that was largely out of his company’s control.

“We don’t control the actions of the big companies. But we’re certainly excited about the work that we’re doing, and we’ve been welcomed‍ back by the medical community as a possible next standard for the treatment of ulcerative colitis,” he added.

The study results, presented in July, were from an eight-week trial of the drug in patients with moderate to severe active ulcerative colitis, a type of chronic inflammation of the intestines.⁤ The company ‍plans to announce full-year treatment results ‍in⁣ the second quarter of⁤ 2026.

2026 ⁢is Full of Catalysts

Abivax has a number of possible ⁢catalysts in 2026. For its⁢ lead product obefazimod, the company plans to file for regulatory approval next year.”We hope this will mean a launch in the third quarter of 2027 in the US,” De Garridel said.

Along with ulcerative colitis,the company has a program ⁣in mid-stage growth for ⁣Crohn’s disease,another inflammatory condition of the digestive ⁤system. It plans ⁤to announce the results of these ‍studies by the end of 2026.

However, the company is currently losing money. As it did not generate revenue, the net loss widened significantly in the nine months of 2025 to‍ 254 ‍million euros, compared to a loss ⁢of 137 million⁣ euros last year. This is mainly due to the cost ⁢of running the one-year clinical trial of obefazimod.

At a Glance

  • Company: Abivax (French Biotech)
  • Stock Performance ⁢(YTD 2025): +1,441% (as of late 2025)
  • Lead Product: obefazimod (for ulcerative Colitis)
  • Key Catalyst: Positive Phase 2b trial data for Obefazimod
  • Next Major Events: Regulatory filing ⁤(2026), Crohn’s Disease trial results (late 2026),⁢ Potential ‍US Launch (Q3 2027)

Editor’s Analysis

Abivax’s dramatic rise is a compelling example of ⁣the potential – and inherent risk‍ – in biotech investing. ⁢The positive trial data for obefazimod clearly‍ ignited investor enthusiasm, ⁢but the company’s⁤ considerable losses highlight the challenges of⁢ bringing a new ⁤drug to⁤ market. The rumors of a takeover⁤ bid add ⁣another layer of complexity. While De Garridel downplays control over such events,the possibility⁣ undoubtedly fuels speculation. The success of obefazimod in Crohn’s disease will be crucial for long-term sustainability.

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