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Fixed-Duration Therapy for CLL: Side Effects & Costs - News Directory 3

Fixed-Duration Therapy for CLL: Side Effects & Costs

December 12, 2025 Jennifer Chen Health
News Context
At a glance
  • * Ianalumab shows promise: The drug Ianalumab may allow patients with Chronic lymphocytic Leukemia (CLL) to stop continuous daily treatment with Ibrutinib.
  • * Shazia Nakhoda, MD (Fox Chase Cancer Center): Highlights the excitement around this data, emphasizing the potential to address both the physical and financial toxicity of long-term continuous...
  • * Presented at: ASH Annual Meeting and Exposition, December 6-9, 2025, Orlando.
Original source: healio.com

Here’s a summary of the article, focusing on key data:

Key Findings:

* Ianalumab shows promise: The drug Ianalumab may allow patients with Chronic lymphocytic Leukemia (CLL) to stop continuous daily treatment with Ibrutinib.
* Fixed-duration therapy benefits: Using fixed-duration therapies (like Ianalumab possibly enabling) can definitely help overcome the long-term side effects and financial burden associated with continuous BTK inhibitor therapy (like ibrutinib).

Expert Opinion:

* Shazia Nakhoda, MD (Fox Chase Cancer Center): Highlights the excitement around this data, emphasizing the potential to address both the physical and financial toxicity of long-term continuous treatment.

Study Details:

* Presented at: ASH Annual Meeting and Exposition, December 6-9, 2025, Orlando.
* Reference: Al-Sawaf O, et al. abstract 1.

Disclosures:

* Dr. Nakhoda has financial relationships with several pharmaceutical companies (Serb Pharmaceuticals, AstraZeneca, BeOne Medicines, and Genentech) including research funding and honoraria.

Source:

* healio Interviews.

Healio AI Promotion: The article also includes a promotion for Healio AI, a tool that allows users to ask clinical questions and access a knowledge base including PubMed, trials, guidelines, and Healio’s news coverage.

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