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FPSAD & PI-RADS for Clinically Significant Breast Cancer Diagnosis

September 29, 2025 Lisa Park - Tech Editor Tech

Okay, here’s ‌a breakdown of the⁣ citations provided,⁢ formatted‌ for easier ‌readability.I’ve included the ⁢key⁣ information for each:

1. yusim I, et al.​ (2020). Sci Rep, 10(1), 20015. https://doi.org/10.1038/S41598-020-76786-9
* Focus: Prostate specific antigen⁢ density and predicting clinically significant ⁤prostate cancer.

2. Choe ‍S, et al. (2023). Urology, 171, 172-178. PMID: ⁤36152871. https://doi.org/10.1016/j.urology.2022.09.007
* Focus: Comparing MRI ‌vs. transrectal ultrasound for prostate volume/PSAD ‍estimation and impact on ⁤cancer detection.

3. Xu B, et al.(2021). Front Oncol, 11, ‍1-18. ‍https://doi.org/10.3389/FONC.2021.730638
⁤ * Focus: ‌metabolomics profiling to differentiate prostate cancer from benign prostatic hyperplasia in ​the PSA gray ⁤zone.

4. Ko ⁤YH, Bh K. (2022). World J ‌Mens Health, 40(4), 543-550.
* Focus: Questioning the applicability of Western prostate cancer screening guidelines⁤ to Asian men.

5.Scialpi‌ M, et al. (2023). Clin Imaging,⁤ 94, 108-115. https://doi.org/10.1016/J.Clinimag.2022.11.013
* Focus: comparing simplified vs. multiparametric ⁢MRI (PI-RADS) for index lesion detection in multifocal prostate cancer.

6. Wen J, et al. (2022). front Oncol, 12, 861928. https://doi.org/10.3389/FONC.2022.861928
⁢ *‌ Focus: Combining PI-RADS v2.1 with prostate-specific antigen density for detection of prostate cancer in the peripheral zone.

7. Zhang Y,⁤ et al.(2023). Eur Urol Oncol,6(2),123-131.⁤ DOI: 10.1016 / j.euo.2022.11.007
⁤ * Focus: ‍ Prostate cancer detection in the PSA gray⁣ zone using PSA density⁣ combined with PI-RADS v2.

8. Peng Z,⁣ et⁢ al. (2024). Small ⁣Methods, 8(10), e2301684. ‌PMID: 38258603. https://doi.org/10.1002/smtd.202301684
* Focus: Identifying ⁣high Gleason ​score prostate cancer using ‍prostate fluid metabolic fingerprinting.

9. Haroun AA, et al. (2011). Saudi J Kidney Dis Transpl, ⁣22(2), 291-297.
* Focus: Utility of free prostate specific antigen and related ​parameters in​ diagnosing prostate cancer.

10. Naya Y, et al. ‍(incomplete citation) Urology.
* focus: Volume⁢ indexes ⁤of prostate-specific⁢ antigen enhancing prediction of extraprostatic disease.

Key Themes/Observations:

* PSA Density: A recurring theme is the use of Prostate Specific​ Antigen Density (PSAD)‌ as a‌ tool to improve prostate cancer detection, particularly in the “gray zone” (where PSA levels are ⁤borderline).
* PI-RADS: ‌ The PI-RADS (Prostate Imaging reporting and Data System) scoring system for MRI is ‌frequently used and evaluated in‌ thes studies.
* Metabolomics: Some ⁤research explores ⁤the use of metabolomics (studying small molecule chemical fingerprints) to differentiate between cancer and benign ⁣conditions.
* MRI advancements: Studies are comparing different MRI techniques ​to improve detection and characterization of prostate cancer.

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