GaGe Digitizers in Pharma & MedTech Research
- This research combined photoacoustic ophthalmoscopy and autofluorescence imaging to measure quantities of melanin and lipofuscin pigments in the retina.
- Challenge: AMD, a leading cause of blindness, is associated with changes in retinal pigments like melanin and lipofuscin.
- How GaGe digitizers were used: Pulsed laser light reflections from the retina were directed into an avalanche photodiode, and the output voltage was obtained using a Gage...
Revolutionary Dual Imaging of Retinal Health: Melanin and Lipofuscin in Real-Time
This research combined photoacoustic ophthalmoscopy and autofluorescence imaging to measure quantities of melanin and lipofuscin pigments in the retina. These pigment quantities may characterize the development of age-related macular degeneration (AMD) in the eye.
Challenge: AMD, a leading cause of blindness, is associated with changes in retinal pigments like melanin and lipofuscin. Customary imaging methods struggle to concurrently and comprehensively visualize both pigments in living organisms.
How GaGe digitizers were used: Pulsed laser light reflections from the retina were directed into an avalanche photodiode, and the output voltage was obtained using a Gage Cobra CS22G8 (2-channels, 8-bits, 2 GS/s). Acoustic energy emitted from the retina was detected by a custom ultrasonic transducer in contact with the eye.This transducer’s output voltage was digitized using a Gage Cobra CS14200 (2-channels, 14-bits, 200 MS/s).
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