Glycosylation Enzyme Selectivity in Mouse Kidneys for Disease Research
- * Researchers have discovered that the glycosylation enzyme GnT-V exhibits selectivity in modifying glycoprotein substrates within mouse kidneys.
- * The research could enable accurate prediction of glycan structures for each glycoprotein in cells.
- * The findings are published in iScience (2025) by Reina F.
HereS a summary of the provided text:
Key Findings:
* Researchers have discovered that the glycosylation enzyme GnT-V exhibits selectivity in modifying glycoprotein substrates within mouse kidneys.
* This selectivity impacts the structures of glycans (sugar molecules) attached to glycoproteins.
Potential Implications:
* The research could enable accurate prediction of glycan structures for each glycoprotein in cells.
* This understanding could eventually lead to the ability to modify glycans for therapeutic purposes (treating diseases).
Source:
* The findings are published in iScience (2025) by Reina F. Osuka et al. (DOI: 10.1016/j.isci.2025.113894)
* The details was provided by the Institute for Glyco-core Research (iGCORE).
Date:
* The research was published/retrieved on November 7, 2025.