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GlycoTARGET - Campusa: Funding by La Caixa Foundation - News Directory 3

GlycoTARGET – Campusa: Funding by La Caixa Foundation

December 10, 2025 Jennifer Chen Health
News Context
At a glance
  • An international consortium led by CIC bioGUNE has secured funding from teh 'la⁢ Caixa' Foundation to develop novel cancer immunotherapies targeting glycans, complex sugar structures, on cancer cells.
  • The GlycoTARGET project, uniting institutions in Spain adn Portugal, ⁣aims to overcome⁢ longstanding challenges in cancer immunotherapy by focusing on glycans.
  • "The project seeks to overcome the immunogenicity⁢ barriers that ‍for years have‍ limited new therapies and, at the same time, explore the true scope of glycans and‌ other...
Original source: ehu.eus

GlycoTARGET Project receives‍ Funding to Advance cancer immunotherapy

Table of Contents

  • GlycoTARGET Project receives‍ Funding to Advance cancer immunotherapy
    • Project Overview:⁢ Harnessing Glycans for Cancer Treatment
      • glycotarget: ⁢Key Facts
    • Funding and Collaboration
    • Researcher ‌Profile:‌ Edurne rujas

An international consortium led by CIC bioGUNE has secured funding from teh ‘la⁢ Caixa’ Foundation to develop novel cancer immunotherapies targeting glycans, complex sugar structures, on cancer cells.

December 7, 2023

Project Overview:⁢ Harnessing Glycans for Cancer Treatment

The GlycoTARGET project, uniting institutions in Spain adn Portugal, ⁣aims to overcome⁢ longstanding challenges in cancer immunotherapy by focusing on glycans. These complex carbohydrates, often overlooked as immunological targets, ​are abundant on the surface of ​cancer cells. The project ⁢will leverage advanced nanotechnology to transform these glycans into viable therapeutic targets and boost the immune​ system’s ability to recognize and destroy cancer.

“The project seeks to overcome the immunogenicity⁢ barriers that ‍for years have‍ limited new therapies and, at the same time, explore the true scope of glycans and‌ other complex antigens as possible immunological targets,”⁤ explained edurne Rujas, the ⁤principal researcher at the University of the Basque Country (EHU).

glycotarget: ⁢Key Facts

  • What: An international research project developing cancer immunotherapies targeting glycans.
  • Who: Led by CIC bioGUNE, with ⁤participation from Spanish and ​Portuguese institutions.
  • Funding: Supported by‌ the ‘la Caixa’ ​Foundation‍ through the ‍CaixaResearch call.
  • Why ⁢it Matters: Addresses a significant gap in cancer treatment by targeting ⁢previously inaccessible immunological targets.
  • What’s Next: Ex vivo and in​ vivo studies,adjuvant optimization,and immune response evaluation.

Funding and Collaboration

The ‘la Caixa’ Foundation’s financial⁣ support, awarded through​ the CaixaResearch call, underscores its commitment‌ to high-quality biomedical research ⁣and the integration of⁢ basic and translational science.⁢ The funding will facilitate both ex vivo (laboratory) ⁣and in vivo (animal) studies,⁤ allowing researchers to refine adjuvants – substances that enhance immune responses – and thoroughly evaluate the ​effectiveness of the new therapies.

This project exemplifies the ⁢power of international collaboration, combining ​the scientific​ leadership of ⁤CIC bioGUNE with the complementary expertise of institutions across ‍Spain and Portugal. This collaborative approach is expected⁢ to accelerate the growth of innovative solutions in the​ fight‌ against cancer.

Researcher ‌Profile:‌ Edurne rujas

Edurne​ Rujas⁤ Díez is ​an Ikerbasque​ researcher affiliated with the‌ Faculty of Pharmacy at‌ the ‌University of the⁣ basque ​Country (EHU). Her work focuses‌ on⁢ the ⁢Pharmacy and Pharmaceutical Technology area within the Department ​of Pharmacy and Food Sciences.

– drjenniferchen

The​ GlycoTARGET ‌project represents a promising shift in cancer immunotherapy. ⁤While significant progress has been made with ‍therapies like checkpoint inhibitors,‍ many cancers remain resistant. Glycans offer a largely ​untapped reservoir of⁣ potential targets. The ​challenge⁣ lies in their complexity and often low immunogenicity – meaning the immune system⁤ doesn’t ⁢readily recognize them as foreign. Nanotechnology-based⁢ approaches, as proposed by ‌GlycoTARGET, could be crucial in overcoming these hurdles by enhancing glycan​ presentation to ⁤the immune ‌system and stimulating a robust anti-cancer response. the ‍focus on adjuvant ‍optimization is also critical, as the⁤ right⁢ adjuvant can dramatically improve the efficacy of a glycan-based ‌vaccine or‍ therapy.

This article was ‍last​ updated on December 10, 2023,‍ at​ 09:20 AM PST.

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