Gut-Brain Connection & Probiotics: Mood & Digestion
- Emerging research indicates that probiotics could play a role in managing negative emotions and anxiety.
- The connection between gut health and mental well-being is gaining increased attention.
- Researchers at Leiden University explored the potential of probiotics to influence mood.
probiotics May Ease Anxiety, Negative Feelings
Emerging research indicates that probiotics could play a role in managing negative emotions and anxiety. A study from Leiden University suggests a daily dose of probiotics may lead to a reduction in negative feelings.

Gut Health and Mental Well-being
The connection between gut health and mental well-being is gaining increased attention. While a balanced diet and exercise are commonly recommended,the impact of gut microbes on psychology is a detail often overlooked. The effects of probiotics on mental health have yielded mixed results, but recent findings offer a glimmer of hope.
Leiden University Study
Researchers at Leiden University explored the potential of probiotics to influence mood. Involving approximately 90 young adults, the study administered a daily probiotic supplement for one month.Participants reported feeling significantly less negative emotion within two weeks. This response time is comparable to some anti-depressants, but probiotics appeared to target negative feelings specifically, rather than suppressing all emotions.
The researchers suggest that individuals who are risk-averse or avoidant might particularly benefit from this effect. They emphasize that probiotics are not necessarily a replacement for medication, but they may reduce inflammation that can affect the brain and cause anxiety.
Specific Probiotic Strains
The study utilized a blend of nine probiotic strains, many of which are available in over-the-counter products. These strains include B. bifidum 23, B. lactis 51,52, L. acidophilus 37, L. brevis 63, L. casei 56,L. salivarius 24, and L. lactis 19, 58.
Dietary Sources of Probiotics
Besides supplements, probiotics can be found in various natural foods, including kefir, kombucha, tempeh, kimchi, unpasteurized sauerkraut, and unpasteurized fermented pickles.
The Gut-Brain Connection
The gut plays a crucial role in producing neurotransmitters, wiht some estimates suggesting it manufactures 50% of those needed by the body and brain. A high-speed,two-way connection exists between the gut and the brain,allowing constant dialog. This has led some to call the gut “the second brain.”
Considerations and Caveats
While the Leiden University study offers promising results, the science surrounding probiotics remains somewhat mixed. Some studies suggest limited or even detrimental effects.It’s also possible to overdo it with probiotics, leading to fatigue or anxiety. However, this study reinforces the idea that probiotics, particularly specific strains, can positively influence mood and possibly alleviate anxiety.
