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High Cortisol Linked to 25% of Hard-to-Treat Hypertension Cases - News Directory 3

High Cortisol Linked to 25% of Hard-to-Treat Hypertension Cases

April 17, 2026 Jennifer Chen Health
News Context
At a glance
  • Study reveals that more than a quarter of people with hard-to-treat high blood pressure may have an overlooked hormone problem linked to excess cortisol.
  • The MOMENTUM study found that elevated cortisol—often associated with stress—was present in 27% of patients with resistant hypertension, a condition where blood pressure remains high despite taking three...
  • Researchers note that this hidden hormone imbalance could explain why standard blood pressure medications fail for many patients, offering a new path for diagnosis and treatment.
Original source: cushingsdiseasenews.com

A large U.S. Study reveals that more than a quarter of people with hard-to-treat high blood pressure may have an overlooked hormone problem linked to excess cortisol.

The MOMENTUM study found that elevated cortisol—often associated with stress—was present in 27% of patients with resistant hypertension, a condition where blood pressure remains high despite taking three or more medications.

Researchers note that this hidden hormone imbalance could explain why standard blood pressure medications fail for many patients, offering a new path for diagnosis and treatment.

Nearly 10 million people in the United States are affected by resistant hypertension, according to the study.

At the same time, hypercortisolism is linked to complications including weight gain, muscle loss, and diabetes.

The discovery could lead to new testing and treatments that finally help bring blood pressure under control for patients who have not responded to standard therapies.

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