Sartorius Unveils iQue® 5 HTS Platform: Revolutionizing High-Throughput Cytometry Screening

Sartorius, a leading international partner of life science research and bioprocess solutions, has launched the iQue® 5 High Throughput Screening (HTS) Platform, a next-generation instrument designed to empower scientists with unparalleled speed and adaptability for cytometry-based screening. This advanced platform promises to accelerate drug finding and development by significantly reducing workflow complexity and minimizing downtime.

Accelerating Discovery with Unmatched Speed and Flexibility

the iQue® 5 HTS Platform is engineered to address the critical need for speed in modern scientific research, especially in areas like antibody and cell therapy development. “For scientists driving the next breakthrough in antibody or cell therapy, speed is crucial, and no instrument can rival the speed of the iQue® HTS Platform,” states Jonah Riddell, product Manager of iQue® HTS Systems at Sartorius. “With iQue® 5 we’re delivering the most powerful screening capabilities for modern applications, complete with enhanced software, individual gain setting, and simplified extended operation so scientists can go even further, even faster.”

This re-designed instrument eliminates workflow complexity through advanced software that supports continuous runtimes of up to 24 hours without manual intervention. This extended operational capability is a significant leap forward, allowing for more complete data acquisition and reducing the need for constant user oversight.

Key Innovations for Enhanced Productivity

The iQue® 5 platform incorporates several key innovations aimed at boosting laboratory productivity and ensuring seamless experimental workflows.

Automated Clog Detection and Resolution

A major bottleneck in conventional flow cytometry is the time-consuming process of resolving instrument clogs. The iQue® 5 addresses this challenge with a new automated clog detection system that dramatically reduces downtime. “In traditional flow cytometry, clogs can take over an hour to resolve, significantly impacting lab productivity,” notes Riddell.

The iQue® 5 tackles the clog issue through multiple innovations. Firstly, its improved fluidics are designed to reduce the overall risk of clogs. Secondly, automatic detection alerts the user and pauses the experiment when necessary, preventing further complications. For added peace of mind, an indicator light provides visual confirmation that the system is flowing smoothly, offering scientists greater confidence in their experimental runs.

Simplified Workflow with Integrated Forecyt® Software

The integrated forecyt® software further simplifies the entire screening process.It offers pre-defined templates and enhanced analytics tools specifically designed to handle complex datasets, making it easier for scientists to extract meaningful insights from their experiments. This user-amiable interface streamlines data analysis, allowing researchers to focus more on interpretation and less on complex software navigation.

The Power of Flow Cytometry in High-Throughput Screening

Flow cytometry is a cornerstone technique in biological research,enabling the rapid analysis of physical and chemical characteristics of cells.Its applications are vast,including immunophenotyping,functional assays,and cytokine profiling. For over two decades, the iQue® HTS Platform has been a recognized leader in purpose-built cytometry solutions for high-throughput screening, lauded for its quality and ease of use.

With the introduction of the iQue® 5, Sartorius reaffirms its commitment to providing scientists with cutting-edge tools that accelerate discovery. The platform’s enhanced capabilities in speed, flexibility, and automation are set to redefine the landscape of high-throughput screening, enabling researchers to push the boundaries of scientific understanding and therapeutic innovation.