Infant Bronchiolitis Prevention Campaign 2025-2026
- Here's a breakdown of the information provided about Beyfortus and Synagis, focusing on recommendations and key points:
- * Beyfortus is now the preferred option: For most infants, Beyfortus (nirsevimab) is recommended over Synagis (palivizumab) for preventing RSV (Respiratory Syncytial Virus) infection.
- * Synagis remains a therapeutic option, especially for children who are eligible for it.
Here’s a breakdown of the information provided about Beyfortus and Synagis, focusing on recommendations and key points:
Key Takeaways:
* Beyfortus is now the preferred option: For most infants, Beyfortus (nirsevimab) is recommended over Synagis (palivizumab) for preventing RSV (Respiratory Syncytial Virus) infection.
* simplified Administration: Beyfortus has a simpler injection schedule than Synagis.
* Availability: Beyfortus can be given directly in maternity wards shortly after birth for babies born from September 1, 2025, and is also available through doctors, midwives, and PMI (child protection services).
* cost: Administration in maternity is fully covered. Or else, health insurance covers up to 30%, with full coverage possible through C2S or AME, and additional coverage from supplemental health insurance.
specific Recommendations:
- Infants (Born Feb-Aug 2025 – Catch-up & Sept 1, 2025 onwards - Routine):
* Beyfortus is recommended as a catch-up for babies born between February and August 2025.* Beyfortus is recommended as a single dose directly after birth for babies born on or after September 1, 2025.
- Children Under 24 Months (Second RSV Season & Vulnerable):
* Beyfortus is recommended for children under 24 months who are entering their second RSV season and are considered vulnerable due to:
* Recent treatment (within the last 6 months) for bronchopulmonary dysplasia.
* congenital heart disease with hemodynamic repercussions.
Synagis (Palivizumab):
* Synagis remains a therapeutic option, especially for children who are eligible for it.
* However, the CNPP (National Pediatrics Council) recommends prioritizing Beyfortus for those children due to its simpler administration and comparable safety profile.
* There haven’t been direct studies comparing the effectiveness of Beyfortus vs. Synagis.
In essence, Beyfortus is being positioned as the primary preventative measure against RSV for most infants, with Synagis remaining an option for specific cases.
