Liver Cancer Risk Linked to Popular Weight Loss Diet – 20 Years After MIT Warning
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Keto diet, which is known to be effective for weight loss, has been shown to increase the risk of liver cancer. if a high-fat, low-carbohydrate diet is maintained for a long period of time, liver cells change and become vulnerable to cancer.
According to a Daily Mail report on the 2nd (local time),research results were recently published in the international academic journal cell,showing that a high-fat,low-carbohydrate keto diet can increase the risk of developing liver cancer within 20 years.
the keto diet is a diet that induces a state of ketosis by almost fully limiting carbohydrate intake. Ketosis is a state in which the body burns stored fat for energy, which helps with weight loss.
“When cells are forced to repeatedly deal with stressors, such as a high-fat diet, they respond in a way that helps them survive, but this also increases the risk of developing cancer,” said Alex Shalek, a professor at the Massachusetts Institute of Technology (MIT) Institute of Medical Engineering Sciences who participated in the study.
The MIT research team fed mice a high-fat diet and observed their liver response using cell analysis technology.
In the early stages, liver cells activated genes that help them survive. It was a method that reduced the possibility of cell death and promoted growth.However, at the same time, genes essential for normal liver function were suppressed.
The researchers found that if liver cells adapt in this way,they are more likely to turn into cancer cells later when harmful mutations occur.
By the end of the study, almost all of the mice fed the high-fat diet had developed liver cancer.
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