Low Sex Hormones Linked to Weak Bones: Health Alert from Daily News

Low sex hormone levels are directly linked to reduced bone mineral density and increased osteoporosis risk, according to recent medical findings reported by Thai news outlet Daily News and supported by current clinical research.

The headline “ฮอร์โมนเพศต่ำส่งผลกระดูกบาง” (Low sex hormones cause thin bones) from Daily News highlights a growing concern in endocrinology and bone health, particularly as populations age and hormone-related bone loss becomes more prevalent. Medical experts have long established that sex hormones such as estrogen and testosterone play a critical role in maintaining bone strength by regulating the balance between bone resorption and formation.

Research from the National Health and Nutrition Examination Survey (NHANES) 2013–2014, which analyzed data from over 1,000 women aged 50 and older, found that increasing estradiol levels and the estradiol-to-testosterone ratio (E2/T ratio) were positively associated with higher bone mineral density. Conversely, a higher testosterone-to-estradiol ratio (T/E2 ratio) correlated with lower bone density and increased fracture risk. These hormonal ratios may serve as more accurate biomarkers than individual hormone levels alone for predicting osteoporosis in postmenopausal women.