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Collaboration Launched to Study Diabetes-Brain Health Link
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Published: October 26, 2025, 5:30 am IST
Last Updated: October 27, 2025, 00:39:37 IST
Key Collaboration Details
The Madras Diabetes Research foundation (MDRF) in Chennai, the Center for Brain Research (CBR) at the Indian Institute of Science (IISc) in Bengaluru, and the UK Dementia Research Institute (UK DRI) have formalized a research collaboration to investigate the complex relationship between diabetes and brain health.A Memorandum of Understanding (MoU) was signed on Saturday, October 25, 2025, to initiate this joint effort.
The Interplay of Metabolic and Brain Health
The collaboration stems from a growing understanding that metabolic diseases,such as diabetes,considerably impact brain health,and conversely,brain health influences metabolic function.This bidirectional relationship underscores the need for an integrated approach to prevention and treatment. As stated by researchers involved, addressing both aspects simultaneously is crucial for optimal health outcomes.
According to the press release, the initiative aims to leverage the expertise of each institution to unravel the underlying mechanisms driving this connection. This includes investigating how diabetes contributes to cognitive decline and neurodegenerative diseases, and how brain health impacts metabolic control.
Focus on Biomarkers and Early Detection
Henrik Zetterberg, Head of the Department of Psychiatry and Neurochemistry at the University of Gothenburg and Group Leader at the UK DRI at UCL Queen Square Institute of Neurology, highlighted the importance of biomarkers in detecting early changes in the brain.He identified Alzheimer’s disease and cerebrovascular disease as the most common causes of dementia. the UK DRI is actively working to develop a globally accessible and affordable biomarker panel for a wide range of neurodegenerative diseases.
Biomarkers offer the potential for earlier diagnosis and intervention, possibly slowing the progression of these debilitating conditions.Alzheimer’s Research UK provides detailed information on different types of dementia and ongoing research efforts.
The Healthy Ageing Clinic and Cognitive Decline
S. Uthra, Senior Scientist at MDRF, described the assessment process at the Healthy Ageing Clinic. Patients aged 60 and above undergo a simple questionnaire evaluating factors including memory function. Data from the clinic demonstrates a clear correlation between age and the percentage of cognitive decline.
Uthra emphasized the critical need to integrate cognitive health into comprehensive diabetes care. This holistic approach recognizes that managing diabetes effectively requires attention to both physical and mental well-being. The MDRF’s work underscores the importance of proactive cognitive screening for older adults, particularly those with diabetes.
Cognitive Decline and Age: MDRF data
| Age Group | Percentage with Cognitive Decline (Example Data) |
|---|
