NEJM April 2026: Volume 394, Issue 16 – Medical Research & Articles
- The New England Journal of Medicine’s April 23, 2026, issue (Volume 394, Issue 16) features several research articles, including a study examining the risk of Guillain-Barré Syndrome following...
- A study published in the journal investigated the potential link between laboratory-confirmed dengue infection and the development of Guillain-Barré Syndrome (GBS).
- Research detailed in the issue focuses on the effectiveness of oral nirmatrelvir–ritonavir, a treatment for Covid-19, in higher-risk outpatients.
The New England Journal of Medicine’s April 23, 2026, issue (Volume 394, Issue 16) features several research articles, including a study examining the risk of Guillain-Barré Syndrome following laboratory-confirmed dengue infection, and research on oral nirmatrelvir–ritonavir for Covid-19 in higher-risk outpatients.
Guillain-Barré Syndrome and Dengue Infection
A study published in the journal investigated the potential link between laboratory-confirmed dengue infection and the development of Guillain-Barré Syndrome (GBS). The research provides data on the incidence of GBS following dengue infection, contributing to a better understanding of the neurological complications associated with this viral illness.
Oral Nirmatrelvir–Ritonavir for Covid-19
Research detailed in the issue focuses on the effectiveness of oral nirmatrelvir–ritonavir, a treatment for Covid-19, in higher-risk outpatients. The study examines the outcomes of patients treated with this antiviral medication, providing insights into its clinical benefits and potential impact on disease progression.

The New England Journal of Medicine’s table of contents for the April 23, 2026, issue indicates a range of medical research and clinical studies. The journal covers pages 1561-1664 for this issue.
Other Articles in the Issue
Beyond the studies on dengue and Covid-19, the April 23, 2026, issue of the New England Journal of Medicine includes a variety of other research articles and clinical reports. The journal continues to serve as a leading platform for disseminating cutting-edge medical knowledge to healthcare professionals worldwide.
The journal’s website provides access to previous issues dating back to 1949, allowing researchers and clinicians to explore a comprehensive archive of medical literature. Issues from 2026 are available, with Volume 394 covering the period from January 1, 2026, through April 30, 2026.
The New England Journal of Medicine publishes new issues weekly, providing a continuous stream of updated medical information. The current issue, Volume 394, Issue 16, released on April 23, 2026, is the latest addition to this ongoing resource for the medical community.
